Indianapolis Colts vs San Francisco 49ers
- Oct 24, 2021 - 8:20PM ET
- Levi’s Stadium - Santa Clara, CA
- Rain and Windy, 62°, 16mph
Game Odds
- The San Francisco 49ers (-3.5) are slightly favored as they host the Indianapolis Colts with an Over/Under of 41.5
- The Colts are 2-4 (33.3%) straight up but possess a profitable ATS record of 4-2 (66.7%)
- The 49ers are 2-3 (40.0%) straight up and 1-4 (20.0%) against the spread
- The 49ers are hitting the UNDER 60.0% (3-2) of the time, while the Colts are 3-3
Previous Matchups
- The Colts are currently riding a 4-game winning streak over the San Francisco 49ers dating back to Oct 9, 2005
- This is the first time these two teams have faced off this season
- The Colts have covered 5 of the last 7 games (71.4%) against the 49ers
- The UNDER has hit 3 of the last 5 games (60.0%)
Key Players
- Today’s game features Carson Wentz. He is averaging 257.5 yards per game (13th in the league). Our partners at PointsBet have the player pass yards prop set at 190.5, which is drastically lower (67.0 pass yards) than the average pass yards per game for Wentz which could indicate good value
- Jonathan Taylor (ranked 6th in rush yards) and Eli Mitchell (ranked 15th in rush yards) will cover plenty of ground in today’s game. Rushing props are available at PointsBet for both Taylor (o/u 68.5 rush yards) and Mitchell (o/u 61.5 rush yards). The better value may be Taylor with his prop coming in 10.2 OVER his normal game average
- Deebo Samuel averages 109.6 receiving yards per game, which ranks 2nd in the league. The receiving yards prop at PointsBet may be an excellent value as Samuel‘s average sits quite a bit OVER the current prop line of 60.5
Injuries - Indianapolis Colts
- OUT: J.J. Nelson, Dezmon Patmon, T.J. Carrie, Quartney Davis, Skai Moore, Nick Nelson, Sam Ehlinger, Parris Campbell, Jordan Wilkins, Robert Windsor and Rodrigo Blankenship.
- Questionable: Rock Ya-Sin, Andrew Sendejo and Kemoko Turay.
Injuries - San Francisco 49ers
- OUT: Trey Lance, Dre Greenlaw, Raheem Mostert, George Kittle, Tarvarius Moore, Jeff Wilson, Jalen Hurd, Richie James, Jordan Willis, Robbie Gould and Jason Verrett.
Head Ref - Craig Wrolstad
- The AWAY team is 15-6 (71.4%) against the spread this season when Craig Wrolstad is part of the crew
- Favorites are 11-10 (52.4%) against the spread this season when Craig Wrolstad is on the field
- The OVER is 11-10 (52.4%) this season when Craig Wrolstad heads up the official crew
