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Ravens vs. Colts prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

The Indianapolis Colts and the Baltimore Ravens open their 2026 campaigns at Lucas Oil Stadium Sunday looking to rebound from disappointing finishes last season.

Both teams finished 8-9. The Ravens’ season never really got off the ground and once it ended they made a change at the top of the food chain. For the first time since 2008, John Harbaugh will not be roaming the Ravens’ sideline. First-year head coach Jesse Minter replaces the veteran Harbaugh. His time in Baltimore may certainly have run its course, but if you are looking for a tangible reason, look no further than the defense. It was a unit that was not the punishing group it once was. The Colts were one of the surprise teams of 2025 until Daniel Jones tore his Achilles. His performance will determine whether Indianapolis is a genuine playoff contender or remains stuck around .500. If they fail to contend in 2026, head coach Shane Steichen will find himself seeking his next opportunity.

Let’s dive into the numbers and see if we can’t find a sweat or two.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game details and how to watch Ravens vs. Colts

  • Date: Sunday, September 13, 2026
  • Time: 1PM ET
  • Site: Lucas Oil Stadium
  • City: Indianapolis, IN
  • TV/Streaming: CBS

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Latest Game Odds for Ravens vs. Colts

The latest odds as of Friday courtesy of DraftKings:

  • Moneyline: Baltimore Ravens (-175), Indianapolis Colts (+145)
  • Spread: Ravens -3.5
  • Total: 47.5

This line sits right where it opened. The Total, however, has dipped a couple points since opening at 49.5.


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Rotoworld Bet Best Bets

Expert picks & predictions for Ravens vs. Colts

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, betting trends, and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Sunday’s game between the Ravens and the Colts:

  • Moneyline: Rotoworld Bet is staying away from a play on the Moneyline
  • Spread: Rotoworld Bet is leaning towards a play on the Colts +3.5.
  • Total: Rotoworld Bet is recommending a play on the Total UNDER 47.5.

Ravens vs. Colts betting trends and stats

  • The Colts were 8-7-2 against the spread this season
  • The Ravens were 6-11 against the spread last season
  • Indianapolis was 9-8 to the OVER last season
  • Baltimore was 11-6 to the OVER last season

Quarterback matchup for Ravens vs. Colts

  • Ravens: Lamar Jackson
    2025 Statistics: 13GP, 2549 Passing Yards, 21 TDs, 7 INTs, 62.7 QBR
  • Colts: Daniel Jones
    2025 Statistics: 13GP, 3101 Passing Yards, 19 TDs, 8 INTs, 63.0 QBR

Top Playmakers: Ravens vs. Colts

Baltimore Ravens

  • WR Zay Flowers
    2025 Statistics: 17GP, 86 Receptions on 118 Targets for 1211 Yds, 5 TDs
  • TE Mark Andrews
    2025 Statistics: 17GP, 48 Receptions on 70 Targets for 422 Yds, 5 TDs
  • RB Derrick Henry
    2025 Statistics: 17GP, 307 carries for 1595 Yds, 16 TDs

Indianapolis Colts

  • WR Alec Pierce
    2025 Statistics: 15GP, 47 receptions on 84 targets for 1003 Yds, 6 TDs
  • TE Tyler Warren
    2025 Statistics: 17GP, 76 receptions on 112 targets for 817 Yds, 4 TDs
  • RB Jonathan Taylor
    2025 Statistics: 17GP, 323 carries for 1585 Yds, 18 TDs

Ravens vs. Colts Injury Update

Baltimore Ravens

  • DT Nnamdi Madubuike (neck) is listed as questionable for Sunday’s game
  • LB Teddye Buchanan (knee) is listed as questionable for Sunday’s game
  • WR Devontez Walker (groin) is listed as questionable for Sunday’s game

Indianapolis Colts

  • WR Alec Pierce (heel) is listed as questionable for Sunday’s game
  • CB Cam Taylor-Britt (susp.) is listed as questionable for Sunday’s game

Rotoworld still has you covered with all the latest and tools for the NFL, including game predictions, player props, futures, and trends!

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