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Top Premier League storylines for Week 6

Chelsea v West Ham United - Premier League

LONDON, ENGLAND - APRIL 08: Pablo Zabaleta of West Ham United tries to stop Eden Hazard of Chelsea during the Premier League match between Chelsea and West Ham United at Stamford Bridge on April 8, 2018 in London, England. (Photo by Catherine Ivill/Getty Images)

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Six Premier League teams faced midweek European contests, with different degrees of success and effort expended by their stars.

[ STREAM: Watch every PL match live ]

Spurs and Man City lost, while Manchester United and Arsenal posted easy wins. Chelsea didn’t have its best finishing boots but won while resting Eden Hazard, and Liverpool won despite a rough night for its best player in Mohamed Salah.

How will that affect the sides when they face decided underdogs this weekend in England and Wales?

Slumping Spurs head south to stop the rot
Brighton and Hove Albion vs. Tottenham Hotspur — 12:30 p.m. ET Saturday on NBC [ STREAM ]

Three-straight losses for Spurs under Mauricio Pochettino; Not something we’ve ready too often, or at all. But the Tottenham boss admits his slumping team could use a break that isn’t coming, especially in the case of Harry Kane. Brighton hasn’t taken it easy on anyone this season, but can be broken down and is coming off a pair of 2-2 ties. Goals at the Amex?

Chelsea returns from Greece for London Derby
West Ham United vs. Chelsea— 8:30 a.m. ET Sunday on NBCSN [ STREAM ]

Eden Hazard and David Luiz were able to rest while Alvaro Morata and Chelsea produced plenty of chances but only one goal at PAOK on Thursday. West Ham had some marvelous moments in attack in getting Manuel Pellegrini a much needed win against Everton last week, and won’t be thinking of anything other than a result when the Blues come back to England for Sunday morning’s kickoff.

Everton hopes to take advantage of weary Arsenal
Arsenal vs. Everton— 11 a.m. ET Saturday on NBCSN [ STREAM ]

Meanwhile, many of Arsenal’s stars rested or played subs roles in Thursday’s defeat of Vorskla Poltava. And the Gunners were home for that tilt, where they’ll remain for the visit of Marco Silva’s Toffees. Everton gets Richarlison back from his red card suspension, and hopes that will help a season that went from “unbeaten in four” to “one win in five” with last week’s loss to West Ham.

Liverpool aims to stay perfect vs. rising Southampton
Liverpool vs. Southampton — 10 p.m. ET Saturday on NBCSN [ STREAM ]

The 5-0 Reds overcame a blown 2-0 lead against Paris Saint-Germain at midweek, and now will face a Saints side which will be missing its top striker (Danny Ings is ineligible due to Liverpool being his parent club). It’s a match that screams trap game, if only because it’s that hard to imagine Saints getting much from Anfield.

Portuguese bosses match wits at Old Trafford
Manchester United vs. Wolves — 10 a.m. ET Saturday on NBC Gold [ STREAM ]

Jose Mourinho’s men are playing well, with captain Paul Pogba almost certainly the best player on the pitch in a pair of recent wins over Young Boys and Watford. Enter Wolverhampton Wanderers, who are playing some attractive football under Mourinho’s countryman Nuno Espirito Santo. This one has the earmarks of a beauty, assuming Mourinho continues to play attack-minded football. Is that too much of an assumption, given the busy week for his Red Devils?

Follow @NicholasMendola