Game No. 2 on Thanksgiving is shaping up to be an elimination game as Dak Prescott and the Dallas Cowboys (5-5-1) host Patrick Mahomes and the Kansas City Chiefs (6-5). Each rallied late to win last weekend to remain on the perimeter of the playoff picture, but a loss this week will potentially be lethal. Dallas rallied from 21 down to Philadelphia to knock off the Eagles on a last second field goal from Brandon Aubrey and the Chiefs forced overtime and eventually knocked off Jonathan Taylor and the Colts.
The Chiefs’ numbers are solid on both sides of the ball, ranking seventh overall on both offense and on defense. The Cowboys are hoping their defense plays as it has the last two weeks. Since the trade deadline Dallas ranks fifth allowing an average of 288 yards per game. Like the Chiefs, Dak Prescott and co. are elite on offense. Both teams average over 25 points per game. Only the Patriots (3142 yards) have thrown for more yardage than the Cowboys (3040) and the Chiefs (2977).
Key matchup: Travis Kelce vs. Dallas’ Linebackers
Kelce has been heating up of late catching 23 passes for 299 yards over the past four games. That’s an average of 13 yards per catch. Rashee Rice is stretching the field which has meant more and more room underneath for Kelce and he has turned that extra space into large chunk plays.
Key matchup No. 2: George Pickens vs. Kansas City secondary
Pickens has been elite this season and combined with CeeDee Lamb to form the top receiving tandem in the NFL. Assuming Trent McDuffie shadows Lamb, it will be incumbent on the rest of the secondary to try and limit Pickens.
Lets dive further into the numbers that are a part of this matchup.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Chiefs vs. Cowboys live Thursday
- Date: Thursday, November 27, 2025
- Time: 4:30PM EST
- Site: AT&T Stadium
- City: Detroit, MI
- Network/Streaming: CBS
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Game odds for the Chiefs vs. the Cowboys
The latest odds as of Monday courtesy of DraftKings:
- Moneyline: Kansas City Chiefs (-170), Dallas Cowboys (+142)
- Spread: Chiefs -3.5
- Total: 51.5 points
This game opened at Chiefs -3.5 with the Game Total set at 52.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for Chiefs vs. Cowboys
- Chiefs Starting QB: Patrick Mahomes
Last Game: 11/23 vs. Indianapolis – 29-46, 352yds, 0TDs, 1INT, Sacked 4 times, 4 carries for 30yds rushing
Season: 11GP, 262-407, 2957yds, 18TDs, 7INTs, Sacked 24 times, 52 carries for 318yds rushing
- Cowboys Starting QB: Dak Prescott
Last Game: 11/23 vs. Philadelphia – 23-36, 354yds, 2TDs, 1 INT, Sacked 1 time, 5 carries for 9yds rushing
Season: 11GP, 276-398, 2941, 23TDs, 7INTs, Sacked 17 times, 38 carries for 126yds rushing
Chiefs at Cowboys team stats, betting trends
- The Cowboys are 34-22-1 all-time on Thanksgiving
- The Cowboys are 3-2 ATS at home this season and 6-5 ATS overall this season
- The OVER has cashed in 7 of Dallas’ 11 gamesthis season (7-4)
- The Chiefs are 1-3 ATS on the road this season and 5-5-1 ATS overall this season
- The OVER has cashed in just 3 of the Chiefs’ 11 games this season (3-8)
- George Pickens has 18 receptions for 290 yards including 2 TDs over the last 2 games
Chiefs Player Injuries
- RB Isiah Pacheco (knee) is listed as questionable for Thursday’s game
- RG Trey Smith (ankle) is listed as questionable for Thursday’s game
- TE Noah Gray (concussion) is listed as questionable for Thursday’s game
Cowboys Player Injuries
- OT Tyler Guyton (ankle) is listed as questionable for Thursday’s game
- OG Hakeem Adeniji (illness) is listed as questionable for Thursday’s game
Rotoworld Best Bets
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Chiefs and the Cowboys
- Moneyline: Rotoworld Bet is leaning towards a play on Dallas on the Moneyline.
- Spread: Rotoworld Bet is recommending a play ATS on Dallas +3.5.
- Total: Rotoworld Bet is staying away from a play on the Game Total of 51.5.
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