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Texans at Seahawks - MNF prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

The Houston Texans (2-3) are in Seattle tonight to take on the Seahawks (4-2) in the second half of tonight’s Monday Night Football doubleheader.

C.J. Stroud and the Texans have won two in a row after starting the season 0-3 but they cannot rest on their laurels. Only six teams have made the playoffs after starting the season 0-3…but the Texans were the last team to do it back in 2018. They need a win to remain within eye shot of the Colts who sit atop the AFC South while Sam Darnold and the Seahawks have started the season strong but have to keep winning to keep pace with the Rams and 49ers in order to remain tied atop the NFC West.

Lumen Field used to be at or near the top of the list of the toughest and loudest environments for a visiting team, but this season both of Seattle’s losses have come at home. Seattle’s attempt to get back to .500 at home will not be easy, though, as the Texans return to the field from their bye week while Darnold and co. were in action in Jacksonville last week. The good news? Seattle has won nine straight away from Lumen Field.

Lets dive into the numbers for the final game of Week 7 in the NFL and see if we can find an advantage or two.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Texans vs. Seahawks live Monday

  • Date: Monday, October 20, 2025
  • Time: 10:00PM EST
  • Site: Lumen Field
  • City: Seattle, WA
  • Network/Streaming: ESPN

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Texans at the Seahawks

The latest odds as of Monday courtesy of DraftKings:

  • Moneyline: Houston Texans (+140), Seattle Seahawks (-166)
  • Spread: Seahawks -3
  • Total: 41.5 points

This game opened at Seahawks -3.0 with the Game Total set at 42.0.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Houston at Seattle

  • Texans Starting QB: C.J. Stroud
    Last Game: 10/5 at Baltimore - 23-27, 244yds, 4TDs, 0 INTs, Sacked 2 times, 1 carry for 30yds rushing
    Season: 5GP, 102-144, 1076yds8 TDs, 3 INTs, Sacked 12 times, 18 carries for 122yds rushing
  • Seahawks Starting QB: Sam Darnold
    Last Game: 10/12 at Jacksonville - 16-27, 295yds, 2 TDs, 0 INTs, Sacked 1 time, 4 carries for 2yds rushing
    Season: 6GP, 114-161, 1541yds, 11 TDs, 3 INTs, Sacked 7 times, 7 carries for 40yds rushing

Texans at Seahawks team stats, betting trends

  • The Seahawks have won 8 of their last 10 home games against teams with losing records
  • The Seahawks are 4-1 against the spread in their last 5 games
  • The Under is 4-1 in the Texans’ last 5 games
  • Sam Darnold is leading the NFL in yards per attempt (9.6)
  • The Texans are looking to become the 5th team since 1990 to win 3 straight games after starting a season 0-3 (2018 Texans, 2011 Chiefs, 2000 Steelers, 1998 Bills)

Texans Player Injuries

  • WR Christian Kirk (hamstring) has been ruled OUT for tonight’s game
  • RB Denico Autry (knee) is listed as questionable for tonight’s game
  • CB Alijah Huzzie (knee) has been ruled OUT for tonight’s game

Seahawks Player Injuries

  • RT Josh Jones (ankle) is questionable for tonight’s game
  • CB Devon Witherspoon (knee) is questionable for tonight’s game
  • S Julian Love (hamstring) is questionable for tonight’s game
  • LB Derick Hall (oblique) has been declared OUT for tonight’s game

Rotoworld Bet Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for tonight’s game between the Texans and the Seahawks:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Houston Texans at +3.5.
  • Total: NBC Sports Bet is staying away from a play on the Game Total of 41.0.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)