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Titans at Raiders prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

Two struggling franchises meet Sunday in Sin City as the Las Vegas Raiders (1-4) host the Tennessee Titans (1-4).

Despite their struggles for much of the season, Cam Ward and Tennessee come to town with a little momentum following last week’s improbable 22-21 win over Arizona. Tennessee scored the final 16 points in the game (all in the fourth quarter). Rookie Cam Ward passed for 265 yards and Tony Pollard rushed for 67 in the win which snapped a 10-game losing streak for the Titans.

The Raiders won against New England in Week 1 but are without a win since averaging just under 16 points per game in those four losses. Last Sunday they were mauled by Daniel Jones and the Indianapolis Colts, 40-6. Fans are calling for the removal of Geno Smith as QB1, but will Kenny Pickett really be an upgrade? No doubt this is not what Pete Carroll envisioned for his return to an NFL sideline.

Lets take a deeper dive into this week’s matchup between the Titans and the Raiders.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Titans at Raiders live Sunday

  • Date: Sunday, October 12, 2025
  • Time: 4:05PM EST
  • Site: Allegiant Stadium
  • City: Las Vegas, NV
  • Network/Streaming: FOX

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Tennessee Titans at the Las Vegas Raiders

The latest odds as of Thursday courtesy of DraftKings:

  • Moneyline: Tennessee Titans (+180), Las Vegas Raiders (-218)
  • Spread: Raiders -3.5
  • Total: 41.5 points

This game opened at Raiders -6.5 with the Game Total set at 41.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Tennessee at Las Vegas

  • Titans Expected Starting QB: Cam Ward
    Last Game: 10/5 at Arizona - 21-39, 265yds, 0 TDs, 1 INT, Sacked 2 times, 5 carries for -6yds
    Season: 5GP, 85-164, 879yds, 2 TDs, 3 INTs, Sacked 19 times, 14 carries for 36yds
  • Raiders Expected Starting QB: Geno Smith
    Last Game: 10/5 at Indianapolis, 25-36, 228yds, 0 TDs, 2 INTs, Sacked 4 times, 3 carries for 8yds
    Season: 5GP, 106-163, 1176yds, 6 TDs, 9 INTs, Sacked 16 times, 16 carries for 74yds

Titans at Raiders team stats, betting trends

  • The Titans have lost 16 of their last 20 games
  • The Titans failed to cover 7 times on the road last season
  • The Over is 4-1 in the Titans’ last 5 road games
  • Tennessee is 2-3 ATS this season
  • Las Vegas is 1-4 ATS this season
  • Tennessee Game Totals are 3-2 to the OVER this season
  • Las Vegas Game Totals are 2-3 to the OVER this season

Titans Player Injuries

  • WR Bryce Oliver (knee) is questionable for Sunday’s game
  • LB Arden Key (thigh) is questionable for Sunday’s game
  • DT Jeffery Simmons (ankle) is questionable for Sunday’s game
  • WR Van Jefferson (ankle) is questionable for Sunday’s game
  • RB Tyjae Spears (ankle) is questionable for Sunday’s game
  • G Blake Hance (undisclosed) is questionable for Sunday’s game
  • RT JC Latham (undisclosed) is questionable for Sunday’s game
  • DE James Lynch (undisclosed) is questionable for Sunday’s game
  • CB Marcus Harris (undisclosed) is questionable for Sunday’s game
  • FS Kevin Winston Jr. (undisclosed)
    is questionable for Sunday’s game
  • PK Joey Slye (calf) is questionable for Sunday’s game

Raiders Player Injuries

  • CB Eric Stokes (knee) is questionable for Sunday’s game
  • TE Brock Bowers (knee) is questionable for Sunday’s game
  • P A.J. Cole (ankle) is questionable for Sunday’s game

Rotoworld Bet Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Titans and the Raiders:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Tennessee Titans at +3.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 41.5.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)