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Gabriel to Start - Vikings vs. Browns prediction: Odds, expert picks, QBs, injury update, trends, and stats

The storyline for the Browns in London has changed dramatically as Dillon Gabriel has replaced Joe Flacco as QB1 for Cleveland. The rookie out of Oregon steps in for the veteran Flacco who too frequently turned the ball over and whose QBR of 27.0 ranked only ahead of Tennessee rookie Cam Ward.

Gabriel has appeared in two games this season completing three of four passes for 19 yards including one touchdown. When he steps under center for Cleveland’s first drive Sunday, Dillon Gabriel will be the Browns’ 41st different starting quarterback since 1999. For those wondering, that is easily the largest number in the league over that time frame.

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As far as the Vikings are concerned, its amazing how quickly a team’s season all of a sudden reaches a crossroads in the NFL. The Minnesota Vikings (2-2) seem to be at such a point this weekend as they play their second consecutive game in Europe (they were in Dublin, Ireland last weekend) when they take the field in London against the Cleveland Browns (1-3).

The Vikings are in this position following their 24-21 loss last weekend to the Steelers in their first of two consecutive games across the Pond. With games against the Eagles, Chargers, and Lions on the horizon, this game becomes paramount. Carson Wentz gets his third straight start in place of the injured J.J. McCarthy. The veteran is 1-1 since taking over as QB1.

Lets take a deeper dive into this matchup.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Vikings vs. the Browns live Sunday

  • Date: Sunday, October 5, 2025
  • Time: 9:30AM EST
  • Site: Tottenham Hotspur Stadium
  • City: London, England
  • Network/Streaming: NFL Network

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Vikings vs. the Browns

The latest odds as of Wednesday courtesy of DraftKings:

  • Moneyline: Minnesota Vikings (-218), Cleveland Browns (+180)
  • Spread: Vikings -4.5
  • Total: 36.5 points

This game opened at Vikings -5.0 with the Game Total set at 38.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Minnesota vs. Cleveland

  • Vikings Expected Starting QB: Carson Wentz
    Last Game: 9/28 vs. Pittsburgh - 30-46, 350yds, 2 TDs, 2 INTs, Sacked 6 times, 2 carries for 12yds
    Season: 2GP, 44-66, 523yds, 4 TDs, 2 INTs, Sacked 9 times, 4 carries for 16yds
  • Browns Expected Starting QB: Dillon Gabriel
    Last Game: 9/28 at Detroit - 0-1, 0yds, 0 TDs, 0 INTs, Was not Sacked
    Season: 2GP, 3-4, 19yds, 1 TD, 0 INTs, Sacked 0 times

Vikings vs. Browns team stats, betting trends

  • The Vikings are 3-1 to the OVER this season
  • The Browns are 2-2 ATS this season
  • The Browns are 3-1 to the UNDER this season
  • The Vikings are 2-2 ATS this season
  • Dillon Gabriel is the 41st starting quarterback for Cleveland since they returned to the NFL in 1999
Treat Judkins as a 'low-end RB1' rest of season
Matthew Berry and Jay Croucher sift through their Weekend Warriors and Sunday Scaries from Week 4, with a pair of rookie RBs rising while veteran WRs continue to fall.

Vikings Player Injuries

  • QB J.J. McCarthy (ankle) has been declared OUT of Sunday’s game
  • LG Donovan Jackson (wrist) has been declared OUT of Sunday’s game
  • LB Andrew Van Ginkel (neck) has been declared OUT of Sunday’s game
  • TE Ben Yurosek (knee) is listed as questionable for Sunday’s game
  • OT Brian O’Neill (knee) is listed as questionable for Sunday’s game
  • C Ryan Kelly (concussion) is listed as questionable for Sunday’s game

Browns Player Injuries

  • WR Cedric Tillman (hamstring) is listed as questionable for Sunday’s game
  • WR DeAndre Carter (knee) has been placed on IR and has been declared OUT for Sunday’s game
  • LT Jack Conklin (elbow) is listed as questionable for Sunday’s game
  • DT Mike Hall Jr. (knee) is listed as questionable for Sunday’s game

Rotoworld Bet Best Bets

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Vikings-Browns is 'uniquely difficult' to price
Jay Croucher and Drew Dinsick describe the "unique" situation when pricing the Vikings vs. the Browns in Week 5, but believe that Carson Wentz is "high variance enough" to lift Minnesota to victory.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Vikings and the Browns:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Cleveland Browns at +3.5.
  • Total: NBC Sports Bet is recommending a play on the OVER on the Game Total of 36.5.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)