No. 4 Duke (23-2, 12-1 ACC) hosts the Syracuse Orange (15-11, 6-7 ACC) tonight in an ACC tilt at Cameron Indoor Stadium. Jon Scheyer’s Blue Devils are riding a 15-game winning streak and coming off a decisive victory against Clemson. Led by superstar freshman forward Cameron Boozer, who is averaging over 22 points and nine rebounds, Duke enters the contest one game ahead of the Virginia Cavaliers and two ahead of Clemson in the resurgent ACC. Tonight the Blue Devils are heavy favorites to continue their recent dominance over the Orange, having won 10 straight against them.
Syracuse arrives in Durham looking to break that losing streak and enter the conversation as a Bonafide Bubble Team with March just around the corner. Saturday, the Orange rallied late to take down SMU at home, 79-78. Under third-year head coach Adrian Autry, Syracuse is led in scoring by junior J.J. Starling and forward Donnie Freeman. While Syracuse has struggled with consistency this season but have played well their last two games – home wins over Cal and the aforementioned SMU. To pull off the upset, the Orange will need to be remarkably better on the glass where they rank 294th in the nation allowing 36.8 rebounds per game, and shooting the basketball both from deep where they average just seven makes per game (No. 255 in the country) and from the line where they rank 363rd making just 63.8% of their free throws.
This “Big Monday” matchup will likely be decided simply by Duke’s ability to not look past Syracuse and ahead to Saturday’s monster tilt against Michigan. Duke’s balanced attack, boasting top-tier efficiency on both offense and defense, provides as significant a challenge as Syracuse has faced this season. That said, this game offers a crucial Quad 1 opportunity for Syracuse to greatly enhance their resume. For Duke, it’s a must-win for them to maintain control atop the ACC.
Duke has a record of 10-2 in Q1 games and is 5-0 in Q2. Syracuse is 1-6 in Q1 and 3-3 in Quad 2 games. The Blue Devils are ranked No. 2 in KenPom and No. 2 in the NET. Syracuse is ranked No. 69 in KenPom and 69th in the NET.
Lets take a closer look at tonight’s matchup and take into consideration lineups, injuries, and other factors affecting the line and total.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds courtesy of DraftKings recent team performance, player stats, and of course, our predictions, picks best bets for the game from our modeling tools and staff of experts.
Game Details and How to Watch Live: No. 4 Duke vs. Syracuse
- Date: Monday, February 16, 2026
- Time: 7PM EST
- Site: Cameron Indoor Stadium
- City: Durham, NC
- Network/Streaming: ESPN
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Game Odds: No. 4 Duke vs. Syracuse
The latest odds as of Monday courtesy of DraftKings:
- Moneyline: Syracuse Orange (+1700), Duke Blue Devils (-4500)
- Spread: Duke -19.5
- Total: 142.5 points
This game opened Duke -20.5 with the Total set at 143.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NCAA Basketball schedule!
Expected Starting Lineups: No. 4 Duke Blue Devils vs. Syracuse Orange
Duke Blue Devils
- G Dame Sarr
- G Isaiah Evans
- G Caleb Foster
- F Cameron Boozer
- C Patrick Ngongba II
Syracuse Orange
- G J.J. Starling
- G Naithan George
- G Nate Kingz
- F Donnie Freeman
- F William Kyle III
Injury Report: Duke vs. Syracuse
Duke Blue Devils
- Ifeanyi Ufochukwu (undisclosed) has been declared OUT for tonight’s game
- Sebastian Wilkins (redshirt) has been declared OUT for tonight’s game
Syracuse Orange
- Noah Lobdell (undisclosed) has been declared OUT for tonight’s game
- Calvin Russell III (undisclosed) has been declared OUT for tonight’s game
- Ibrahim Souare (undisclosed) has been declared OUT for tonight’s game
- Aaron Womack (undisclosed) has been declared OUT for tonight’s game
Important stats, trends and insights: No. 4 Duke vs. Syracuse
- Duke is 12-0 at home this season
- Syracuse is 2-4 on the road this season
- Syracuse is 14-12 ATS overall this season
- Duke is 13-12 ATS overall this season
- The OVER has cashed in 13 of Duke’s 25 games this season (13-12)
- The OVER has cashed in 5 of Syracuse’s last 7 games and 9 of their last 12 games this season (14-12 overall this season)
- Duke is 10-0 on the Moneyline in their last 10 games against Syracuse
- Duke is 9-1 ATS in their last 10 games against Syracuse
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NCAA calendar based on data points like recent performance, head-to-head player matchups, trends information and projected game totals.
Once the model is finished running, we put its projections next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for tonight’s game between Duke and Syracuse:
- Moneyline: Rotoworld Bet is staying away from a play on the Moneyline
- Spread: Rotoworld Bet is actually leaning towards a play on Syracuse +19.5 ATS
- Total: Rotoworld Bet is leaning towards a play on the Game Total OVER 142.5
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