Campbell went down with what looked like a serious injury in the first half of New England’s win over the Raiders. He did not return to action. Campbell, per Pelissero, will be “week to week” headed into Week 6. The Patriots will likely be without him this weekend against the Jets.

Schefter reached out to the team after a league source told him the Chargers could get upwards of three first-round draft picks in exchange for Herbert. The Chargers source told Schefter the team has “never” discussed the idea of dealing Herbert, even as the Chargers start the season 0-5 and rank near the bottom in almost every offensive category. It would seem unlikely that the Chargers would consider trading Herbert even if they go all in on a rebuild following the 2026 season. Herbert, 28, who ranks 33rd out of 34 qualifying quarterbacks in EPA per drop back this year, is signed through the 2029 season.

With Deebo Samuel sustaining a serious hamstring injury in Week 5 against Seattle, Cooks stepped in and functioned as San Francisco’s No. 2 receiver behind Mike Evans. Cooks was targeted on 17 percent of his pass routes against the Seahawks and caught a touchdown on his only reception. Though Jacob Cowing could mix in with Samuel sidelined, Cooks should be in line for a few targets a game. The well-traveled veteran can be picked up in deeper fantasy formats this week.

Henderson suffered his latest ankle injury in Week 5 against the Raiders. Schefter said Henderson is “regarded as a quick healer, so the Patriots are hoping his return is sooner rather than later.” Still, he could be sidelined for the next few weeks, leaving Rhamondre Stevenson as the team’s clear lead back. Corey Kiner, meanwhile, appears to be in line as the Patriots’ RB2 after seeing seven touches last week against the Raiders. Kiner should be stashed in most 12-team fantasy leagues for now. Stevenson profiles as a top-12 play until Henderson returns.

Adams cashed in on a corner fade from four yards out in the second quarter and ran a beautiful route on a double move slant from five yards out for his second score in the fourth quarter, proving that he remains an elite red zone weapon for an offense that has now attempted 51 or more passes in three straight games. Adams is back to modest target rates following the Week 4 return of Puka Nacua but remains a weekly WR2 due to his red zone acumen, which remains true ahead of a much more forgiving matchup against the Cardinals in Week 6.

Nacua operated as the primary option through the air for a Rams team that attempted more than 50 passes for the third straight game. The veteran alpha was mostly confined to short-area work, something that could be attributed to the groin injury that continues to have his name on the injury report in practice, but that would not keep Nacua from returning another elite WR1 performance. Nacua was also inches away from padding his stat line further after failing to come down with what would have been a 51-yard touchdown reception on the final play of the first half. Nacua and the Rams fall to 2-3 ahead of a Week 6 divisional showdown against the Cardinals, where he will remain one of the top fantasy assets in the league.

Williams has yet to see more than the 16 carries he saw against the Bills this season but the team’s recent pass-heavy nature has left the veteran lead back with six or more receptions in three straight games, including 27 total targets in that span. The elite-level aerial volume made it three consecutive games with 20 or more opportunities for Williams, who continues to return RB1 fantasy weeks while playing in one of the league’s top offenses. Williams remains a middling RB1 ahead of a Week 6 divisional showdown against the Cardinals at home.

It was the third consecutive game in which Stafford attempted 51 passes or more in what has become the most voluminous passing offense in the league. The two powerhouses felt each other out throughout the first half as only 20 combined points per scored before the break. Things would get aggressive for the final 30 minutes as seven combined touchdowns were scored on nine second half possessions, four of which were accounted for by the Rams. Stafford directed a whopping 24 targets toward alpha wide receiver Puka Nacua, who set a career high with 17 receptions in a short-area role. The reigning MVP returned an instant classic performance against the 2024 MVP, ultimately coming up short in overtime following a blocked field goal attempt from Harrison Mevis. The Rams fall to 2-3 ahead of a home matchup against the more forgiving Cardinals in Week 6. Stafford is once again a fantasy QB1 in that matchup.

Cook’s elite rushing line was overshadowed by two fumbles, the second of which was a lost fumble on the team’s first possession of overtime, placing the Rams in position to complete the comeback and steal away the victory. A blocked field goal on what would have been the game-winning kick breathed new life into the Bills, who demonstrated confidence in their lead back by throwing him right back out there on the following possession to eventually win the game. The 26 touches go down as a season high for the veteran back, who found paint for the fourth consecutive game in the thrilling overtime win. Cook remains a top-tier RB1 for fantasy purposes ahead of a Week 6 meeting with the Raiders in Las Vegas.

The two teams mustered only 20 combined points in the first half as they felt each other out. There were only two punts after the break between the two sides, who combined for seven touchdowns on nine combined possessions including five straight touchdowns in the fourth quarter to send the game to overtime. Allen and the Bills took the ball first in the extra frame and quickly found themselves deep in enemy territory following a 57-yard, catch-and-run pass to Khalil Shakir. A James Cook fumble on the next play appeared to shatter Allen’s chances of earning his first career win in overtime, but a blocked 48-yard field goal attempt from Harrison Mevis gave the ball back to the Bills with a chance to win. Two Josh Allen scrambles set up a game-winning, 45-yard field goal for Tyler Bass. Allen ended with the second most yards on the ground of his career as the Bills moved to 4-1 with the wild win. Allen remains the top overall quarterback in fantasy circles ahead of a Week 6 meeting with the Raiders on the road.