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Packers vs. Bears prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

First place in the NFC North is up for grabs Saturday in the Windy City when the Green Bay Packers (9-4-1) visit the Chicago Bears (10-4) at Soldier Field.

Caleb Williams and company lead the NFC North but their playoff hopes - not just their division title hopes but also their playoff hopes suffer a serious blow should they lose to Green Bay. Their schedule makes this game more of a must-win than it does for the Packers. Chicago closes the regular season with games at San Francisco and at home against the Lions. Tough sledding.

A loss by Green Bay puts the Packers one loss or one Chicago win from clinching the NFC North but their schedule is more favorable with a home game against Lamar Jackson and the Ravens and a road game at the Vikings.

Green Bay will take the gridiron without their star pass rusher Micah Parsons. The All-Pro tore his ACL in last weekend’s 34-26 loss to the Broncos in Denver. Who steps up and fills the sudden void in the Packers’ lineup? That will be an adjustment for the Packers especially as they look to slow down the Bears’ rushing attack (ranked No. 2 in the NFL).

The Bears blew out the Browns, 31-3, this past Sunday. Williams threw for 242 yards and a couple touchdowns in the win. Chicago’s defense allowed just 192 yards of Total Offense in the dominant win.

Key Matchups: Bears’ Ground Game vs. Packers’ Rush Defense

Chicago’s strong run game featuring D’Andre Swift and Kyle Monangai will challenge a Packers’ defense that is suddenly without its best player.

Lets dive a bit deeper into the numbers for this week’s NFC North matchup between the Packers and the Bears.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to Watch: Packers vs. Bears live Saturday

  • Date: Saturday, December 20, 2025
  • Time: 8:20PM EST
  • Site: Soldier Field
  • City: Chicago, IL
  • Network/Streaming: FOX

Want to check out the other games on the NFL schedule this week? We’ve got you covered at NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game Odds: Packers at Bears

The latest odds as of Tuesday courtesy of DraftKings:

  • Moneyline: Green Bay Packers (-115), Chicago Bears (-105)
  • Spread: Packers -1.5
  • Total: 46.5 points

This game opened at Packers -2.0 with the Game Total set at 46.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Green Bay at Chicago

  • Packers Starting QB: Jordan Love
    Last Game: 12/14 at Denver, 24-40, 276yds, 1 TD, 2INTs, Sacked 3 times, 3 carries for 29yds rushing
    Season: 14GP, 283-426, 3304yds, 23TDs, 6 INTs, Sacked 21 times, 45 carries for 192yds rushing
  • Bears Starting QB: Caleb Williams
    Last Game: 12/14 vs. Cleveland - 17-28, 242yds, 2TDs, 0INTs, Sacked 3 times, 3 carries for 13yds rushing
    Season: 14GP, 266-459, 3150yds, 21TDs, 6INTs, Sacked 23 times, 68 carries for 334yds rushing

Packers at Bears: Team Stats and Betting Trends

  • The Bears are 9-5 ATS this season
  • The Packers are 6-8 ATS this season
  • The OVER has cashed in 8 of the Packers’ 14 games this season (8-6)
  • The OVER has cashed in 7 of the Bears’ 14 games this season (7-6-1)
Bet on Bears with injuries weakening Packers
Vaughn Dalzell and Drew Dinsick discuss Week 16's NFC North battle between the Bears and Packers and why Green Bay's recent injury troubles could spell doom versus Chicago.

Packers Player Injuries

  • DE Micah Parsons (knee) has been declared OUT for Saturday’s game
  • RT Zach Tom (knee) is listed as questionable for Saturday’s game
  • WR Christian Watson (chest) is listed as questionable for Saturday’s game
  • WR Savion Williams (foot) is listed as questionable for Saturday’s game
  • TE Josh Whyle (concussion) is listed as questionable for Saturday’s game
  • OT John Williams (undisclosed) has been declared OUT for Saturday’s game
  • DE Collin Oliver (undisclosed) has been declared OUT for Saturday’s game
  • S Evan Williams (knee) is listed as questionable for Saturday’s game

Bears Player Injuries

  • WR Rome Odunze (foot) is listed as questionable for Saturday’s game
  • WR Luther Burden III (ankle) is listed as questionable for Saturday’s game
  • QB Tyson Bagent (illness) is listed as questionable for Saturday’s game
  • RB Travis Homer (ankle) is listed as questionable for Saturday’s game
  • LB Tremaine Edmunds (groin) has been designated to return from the IR

Rotoworld Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Packers and the Bears

  • Moneyline: Rotoworld Bet is staying away from a play on the Moneyline.
  • Spread: Rotoworld Bet is leaning towards a play ATS on the Chicago Bears at +1.5.
  • Total: Rotoworld Bet is recommending a play on the UNDER on the Game Total of 46.0.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)