Mike Vrabel returns to Nashville and specifically Nissan Stadium for the first time since being fired as Head Coach of the Titans when the New England Patriots (4-2) take the field against Tennessee (1-5) Sunday.
For the Titans, it is their first game since the firing of Vrabel’s replacement, Brian Callahan. Senior Offensive Assistant Mike McCoy is the Interim Head Coach. The veteran McCoy was the Chargers’ Head Coach for 4 seasons (2013-16), amassing a record of 27-37.
The Titans are looking to avoid starting 1-6 in back-to-back seasons. The primary issue in Tennessee has been the offense. Rookie Cam Ward and the Titans are averaging a mere 13.8 points per game. Only the Browns are scoring fewer points per game 13.7. One potential reason for the futility on offense? The rookie has been sacked a league-high 25 times already this season.
The Patriots will remain atop the AFC East with a win which would be their fourth straight and mark their best 7-game start since 2019 when the Pats started 8-0 enroute to the division title. New England is led by second-year signal-caller Drake Maye. The Super Soph has enjoyed five straight games with 200+ passing yards and a 100+ passer rating.
Lets take a deeper dive into this Week 7 matchup between the Patriots and the Titans.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Patriots at Titans live Sunday
- Date: Sunday, October 19, 2025
- Time: 1:00PM EST
- Site: Nissan Stadium
- City: Nashville, TN
- Network/Streaming: CBS
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Game odds for the Patriots at the Titans
The latest odds as of Thursday courtesy of DraftKings:
- Moneyline: New England Patriots (-345), Tennessee Titans (+275)
- Spread: Patriots -7
- Total: 41.5 points
This game opened at Patriots -6.0 with the Game Total set at 43.0.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for New England at Tennessee
- Patriots Starting QB: Drake Maye
Last Game: 10/12 at New Orleans - 18-26, 261yds, 3 TDs, 0 INTs, Sacked 1 time, 9 carries for 28 rushing yards
Season: 6GP, 131-179, 1522yds, 10 TDs, 2 INTs, Sacked 18 times, 36 carries for 138 rushing yards - Titans Starting QB: Cam Ward
Last Game: 10/12 at Las Vegas - 26-38, 222yds, 1 TD, 1 INT, Sacked 6 times, 0 carries
Season: 6GP, 111-202, 1101yds, 3 TDs, 4 INTs, Sacked 25 times, 14 carries for 36 yards rushing
Patriots at Titans team stats, betting trends
- The Patriots have won 3 in a row while the Titans are on a 6-game home losing streak
- The Titans have 4 total wins in their last 23 games
- Mike Vrabel has 4 wins through 6 games with the Patriots
- The Titans’ last 4 home games have gone OVER the Total
- Titans QB Cam Ward is the 4th straight QB selected No. 1 overall in the draft to see his HC fired during his rookie season (2024 Caleb Williams - Matt Eberflus, 2023 Bryce Young - Frank Reich, 2021 Trevor Lawrence - Urban Meyer)
Patriots Player Injuries
- WR Stefon Diggs (chest) is questionable for Sunday’s game
- CB Charles Woods (knee) is questionable for Sunday’s game
- S Jaylinn Hawkins (hamstring) is questionable for Sunday’s game
- LB Anfernee Jennings (ankle) is questionable for Sunday’s game
- LB Harold Landry III (ankle) is questionable for Sunday’s game
- RT Morgan Moses (undisclosed) is questionable for Sunday’s game
Titans Player Injuries
- LB Arden Key (quad) is questionable for Sunday’s game
- WR Bryce Oliver (knee) is questionable for Sunday’s game
- CB Marcus Harris (calf) is questionable for Sunday’s game
- G Blake Hance (shoulder) is questionable for Sunday’s game
- CB L’Jarius Sneed (quad) is questionable for Sunday’s game
- WR Calvin Ridley (hamstring) is questionable for Sunday’s game
- WR Van Jefferson (ankle) is questionable for Sunday’s game
- PK Joey Slye (calf) is questionable for Sunday’s game
- DE James Lynch (undisclosed) is questionable for Sunday’s game
- S Kevin Winston Jr (undisclosed) is questionable for Sunday’s game
Rotoworld Bet Best Bets
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Drew Dinsick (@whale_capper): New England at Tennessee Game Total OVER 41.5 (-102)
The Patriots’ offense has been so superb lately that they may hit this number themselves but regardless the Titans’ coaching change may pump up that lifeless unit and create a very watchable game that should be lined around 44 in my opinion.
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Patriots and the Titans:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Tennessee Titans at +7.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 42.5.
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● Jay Croucher (@croucherJD)
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