What makes this interesting is that the Guardians are starting right-hander Daniel Espino as the opener for left-hander Foster Griffin. Antonacci usually doesn’t play against lefties, and his being the DH means that the White Sox have more flexibility to pinch-hit for him. There’s a chance that he gets his at-bat in the first inning and then, when his spot in the order comes up again, he could be replaced by Tommy Pham or Brenton Doyle, both of whom started in Game 1, to hit against the left-handed Griffin.