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St. Brown saw a pedestrian first half before the Lions were forced to attack the short-to-intermediate areas of the field against a 4-3, Cover-2-heavy Steve Spagnuolo defense that all but eliminated downfield passing. The 10 targets handily led the team but the modest yardage total ranked behind both Jameson Williams and Sam LaPorta, the latter two of whom each also found the end zone in the loss. St. Brown remains a WR1 in fantasy circles ahead of a Week 7 showdown with the Buccaneers on Monday Night Football.

Pearsall was targeted three times, catching just one pass for zero yards. He did get some looks downfield, but was not quite open for completions. The good news is Pearsall tied Jauan Jennings for snaps on the day, with both receivers seeing 41. He was not limited in his return from a knee injury in terms of snaps, but was a distant No. 4 pass-catching option in the offense. Pearsall currently lies in the fantasy WR4 range for Week 12 against the Panthers.

Brown played only 30 snaps — behind Noah Gray and splitting time with JuJu Smith-Schuster — en route to this line. With Tyquan Thornton also mixing in for some deep shots, Brown looks to be in the FLEX touchdown-or-bust bucket in Week 12 against the Colts.

Operating mainly as a zone receiver in this one, Kelce had a drop, but bounced back with a catch-and-score by scooting past Talanoa Hufanga. The score was his 84th career touchdown, putting him ahead of Priest Holmes on the Chiefs all-time list. After looking mostly like a low-end TE1 early in the season, Kelce has now managed 19 catches for 256 yards and two touchdowns in his last three games. He’ll be a mid-range TE1 against the Colts in Week 12.

Henry also caught 2-of-2 targets for 19 yards. Henry was spelled regularly against the Browns with RBs Keaton Mitchell and Rasheen Ali getting involved early on the first drive. Henry even ceded red zone and green zone snaps to both players. A shove in the back from WR Zay Flowers helped him find the end zone on the Ravens’ fourth drive. Henry deserves credit for getting skinny on a 59-yard run up the middle on the Ravens’ ninth drive, though. The Ravens called his number twice after the long gain, but ultimately settled for a field goal. Henry is an RB1 against the Jets next week.

Seemingly unable to let him win in man coverage with the amount of pressure they were seeing, Rice was relegated to a high-end gadget player against the Broncos. He did manage a team-leading three targets in the red zone, but only turned them into nine yards. We expect better against the Colts next week, where Rice will remain on the WR1 line despite this dud against one of the league’s best defenses.

Jennings tied George Kittle and Christian McCaffrey for the team lead with six targets on the day. He operated as Brock Purdy’s No. 1 wide receiver on the day, catching four passes for 54 yards. He caught the 49ers’ first pass of the game for 25 yards and was routinely available for intermediate targets. With Ricky Pearsall just returning from injury, Jennings remains the best wide receiver option out of the 49ers’ group. He is a WR3 option for Week 12 against the Panthers.

He “added” a minus-5 yard catch on his only target. McLaughlin and Tyler Badie split 16 snaps evenly as foils to RJ Harvey, and McLaughlin lived up to the idea by stealing two red zone touches from Harvey and the game’s only touchdown. McLaughlin isn’t a must-hold through Denver’s Week 12 bye, but he’s certainly got a fantasy pulse again following JK Dobbins’ injury.

Harvey played on 38 of Denver’s 62 offensive snaps, so while Sean Payton wasn’t exactly lying in saying that he’d see a bigger role, he hardly dominated the backfield. He lost the team’s lone touchdown of the game to Jaleel McLaughlin in the red zone. He nearly threw an interception on Denver’s first red zone series. Harvey will return from Denver’s bye as a fantasy RB2 on workload, but any thought of him being ready to explode in JK Dobbins’ absence was put on hold today.

Kittle operated in his usual nearly every-snap role in the offense with Brock Purdy back in the fold, tying the team lead with six targets. Purdy dropped a pass right into his hands for a 30-yard score in the first half; Kittle followed that up with a four-yard receiving score in the third quarter. Without a definitive No. 1 wide receiver, Kittle and Christian McCaffrey are the primary two pass-catchers in the 49ers offense. He is a fantasy TE1 for Week 12 against the Panthers.