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Eagles vs. Packers prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

Monday Night Football this week features two division leaders and NFC powerhouses as Jordan Love, Micah Parsons, and the NFC North leading Green Bay Packers (5-2-1) welcome Jalen Hurts and the NFC East leading Philadelphia Eagles (6-2) to Lambeau Field.

The Eagles’ offense has been clunky at times this season, but it is the best in the Red Zone scoring touchdowns 85% of the time they reach their opponent’s 20-yard line. Hurts has accounted for 20 TDs this season (15-pass, 5-run) to lead Philly’s attack.

The Packers’ offense has not come under the same scrutiny as has the offense of the Eagles, but it has scored fewer points (208-206). The reason may well be due to their play on the other side of the ball. Green Bay’s defense has been stingy. Parsons and co. have held opponents to just under 21 points per game.

Fun Fact: Green Bay seeks payback after their 2024 season began and ended with losses to Philadelphia.

Lets take a deeper dive into Monday Night Football and see where the numbers lead us.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Eagles vs. Packers live Monday

  • Date: Monday, November 10, 2025
  • Time: 8:15PM EST
  • Site: Lambeau Field
  • City: Green Bay, WI
  • Network/Streaming: ABC

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Eagles at the Packers

The latest odds as of Monday courtesy of DraftKings:

  • Moneyline: Eagles (-102), Packers (-118)
  • Spread: Eagles -1.5
  • Total: 45.5 points

This game opened at Packers -3 with the Game Total set at 45.0.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Philadelphia at Green Bay

  • Eagles Starting QB: Jalen Hurts
    Last Game: 10/26 vs. Giants - 15-20, 179yds, 4TDs, 0INTs, Sacked 4 times, 4 carries for 22yds rushing
    Season: 8GP, 151-215, 1677yds, 15TDs, 1INT, Sacked 25 times, 58 carries for 207yds rushing
  • Packers Starting QB: Jordan Love
    Last Game: 11/2 vs. Carolina - 26-37, 273yds, 0TDs, 1INT, Sacked 1 time, 1 carry for 1yd rushing
    Season: 8GP, 177-250, 2071yds, 13TDs, 3INTs, Sacked 11 times, 26 carries for 110yds rushing

Eagles at Packers team stats, betting trends

  • The Eagles have won on 4 of their last 5 games as a road underdog
  • The Eagles are 5-3 ATS this season
  • The Packers are 3-5 ATS this season
  • Jalen Hurts has 20 total TD (15 passing, 5 rushing), 1 INT this season
  • Saquon Barkley rushed for season-high 150 yards last week vs. NYG (his first game with 100+ rush yards this season)
  • Packers have 5 giveaways this season (T2 behind only the Eagles and their 3)
  • Packers have 5 takeaways this season (2nd
    fewest in NFL behind the Jets and their 1)
  • Josh Jacobs has Rushing TDs in 16 of his last 17 games, including the playoffs
NFL Week 10 preview: Eagles vs. Packers
Mike Florio and Chris Simms preview a Monday Night Football duel between the Eagles and Packers, debating if Philadelphia should be favored and sharing why "they know how to win the game and the Packers don't right now."

Eagles Player Injuries

  • CB Jaire Alexander (knee) has been declared OUT of Monday’s game
  • C Cam Jurgens (knee) has been declared OUT of Monday’s game
  • LB Nolan Smith Jr. (triceps) has been activated off the IR and is questionable for Monday’s game
  • C Willie Lampkin (knee) has been activated off the IR and is questionable for Monday’s game

Packers Player Injuries

  • RT Zach Tom (back) is questionable for Monday’s game
  • WR Savion Williams (foot) is questionable for Monday’s game
  • WR Dontayvion Wicks (calf) is questionable for Monday’s game
  • WR Matthew Golden (shoulder) is questionable for Monday’s game
  • CB Nate Hobbs (knee) is questionable for Monday’s game
  • TE Tucker Kraft (knee) has been placed on IR and has been declared OUT for Monday’s game
  • RB Marshawn Lloyd (hamstring) has been activated from IR but is questionable for Monday’s game
  • DE Lukas Van Ness (foot) has been declared OUT of Monday’s game

Rotoworld Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Eagles and the Packers

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Philadelphia Eagles at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 45.5.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)