one quarter of the way through the regular season, the Jacksonville Jaguars (4-1) have to be considered one of the surprises in the NFL in 2025. Tied atop the AFC South with another of the league’s feel-good stories, the Indianapolis Colts, Liam Coen has the Jags beginning to believe in themselves as they prepare to line up against the Seattle Seahawks (3-2) Sunday afternoon.
The Seahawks are flying cross country for the early afternoon kickoff after losing at home to the Bucs last weekend, 38-35. Prior to last weekend, Seattle’s defense had only allowed even 20 points just one time. Baker Mayfield picked them apart with help from rookie wideout Emeka Egbuka. Sam Darnold passed for 341 yards and four touchdowns in the loss.
This past Monday, the Jaguars earned their biggest win of the season knocking off Patrick Mahomes and the Kansas City Chiefs, 31-28. Trevor Lawrence led the Jags to victory throwing for 220 yards including one touchdown and rushing for two others including the game-winner with 23 seconds remaining.
Questions to ponder as you review the underlying numbers in this game:
1) Does Trevor Lawrence continue to show growth under the tutelage of Liam Coen even when facing a top defense like Seattle?
2) Does the Seahawks’ defense rebound this week?
3) Can Sam Darnold keep from turning the ball over against a team that has thrived on causing turnovers?
Lets take a deeper dive into this week’s game between the Seahawks and the Jaguars.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Seahawks vs. Jaguars live Sunday
- Date: Sunday, October 12, 2025
- Time: 1:00PM EST
- Site: EverBank Stadium
- City: Jacksonville, FL
- Network/Streaming: FOX
Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!
Game odds for the Seahawks at the Jaguars
The latest odds as of Sunday courtesy of DraftKings:
- Moneyline: Seattle Seahawks (-110), Jacksonville Jaguars (-110)
- Spread: Jaguars -1.5
- Total: 47.5 points
This game opened at Jaguars -1.0 with the Game Total set at 44.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for Seattle at Jacksonville
- Seahawks Expected Starting QB: Sam Darnold
Last Game: 10/5 vs. Tampa Bay - 28-34, 341yds, 4 TDs, 1 INT
Season: 5GP, 98-134, 1246yds, 9 TDs, 3 INTs, Sacked 6 times, 3 carries for 38yds - Jaguars Expected Starting QB: Trevor Lawrence
Last Game: 10/6 at Kansas City - 18-25, 221yds, 1 TD, 1 INT, Sacked 3 times, 10 carries for 54yds
Season: 5GP, 102-169, 1066yds, 6 TDs, 5 INTs, Sacked 6 times, 25 carries for 86yds
Seahawks at Jaguars team stats, betting trends
- The Seahawks have won 9 of their last 10 road games
- The Seahawks are 3-2 ATS this season
- The Jaguars are 4-1 ATS this season
- Game Totals for Seattle are 3-2 to the OVER this season
- Game Totals for Jacksonville are 3-2 to the OVER this season
Seahawks Player Injuries
- G Josh Jones (ankle) has been declared out of Sunday’s game
- LB Derick Hall (oblique) has been declared out of Sunday’s game
- CB Riq Woolen (concussion) is doubtful for Sunday’s game
- S Julian Love (hamstring) is doubtful for Sunday’s game
- CB Devon Witherspoon (knee) is doubtful for Sunday’s game
- DT Rylie Mills (undisclosed) is out for Sunday’s game
Jaguars Player Injuries
- C Robert Hainsey (hamstring) is doubtful for Sunday’s game
- LB Yasir Abdullah (hamstring) is questionable for Sunday’s game
TE Brenton Strange (quad) has been placed on IR and is out for Sunday’s game
Rotoworld Bet Best Bets
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Drew Dinsick (@whale_capper): Seattle Seahawks ML+104
Sam Darnold has the fewest turnover worthy plays so far this season which will be key in preventing the Jags from creating the game changing turnovers that have fueled their defensive success. Seattles defense on the other hand can completely shutdown the rushing attack and force Trevor Lawrence into his second or third reads which he has struggled with to this point in 2025.
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Seahawks and the Jaguars:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Seattle Seahawks at +1.5.
- Total: NBC Sports Bet is staying away from a play on the Game Total of 46.0.
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Follow our experts on socials to keep up with all the latest content from the staff:
● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)