Castillo served up a leadoff homer to Elly De La Cruz in the first inning. After two scoreless frames, Eugenio Suárez got to him for a solo shot in the fourth. The Reds added a third run on a walk, single, and sacrifice fly in the fifth. Castillo would give the Mariners two more scoreless innings, ending with a quality start. He struck out three. The 33-year-old right-hander will take a 4.85 ERA, 1.33 WHIP, and an 84/30 K/BB ratio across 94 2/3 innings into a start against the Dodgers in Los Angeles next week.