Greenlaw (quad) is expected to play vs. Denver

The 49ers will have their stud left tackle active on Sunday. 49ers LB Dre Greenlaw (quad bruise) is questionable to play. 49ers EDGE Nick Bosa (calf) and DL Mykel Williams (knee) have both been ruled out.

49ers coach Kyle Shanahan said earlier this week that Williams was expected to resume practicing today. The fact that he is on track is a good sign for his Week 4 availability. 49ers LB Dre Greenlaw (bruised quad) is still sidelined.

The 49ers don’t play until Sunday, so we’re assuming Shanahan is referencing when we should first expect Williams to take the practice field this week. Williams suffered what was classified as a stinger in Week 3’s win over the Cardinals, but appears to have avoided any serious injury. Shanahan said the team plans to manage he and LB Dre Greenlaw (quad) throughout the week, and didn’t rule out either player playing in Week 4 against the Broncos.

According to ESPN’s Nick Wagoner, “it was unclear exactly what happened to Evans.” He got hit hard in the sternum on a catch over the middle, but remained in the game for a few plays before needing help from the training staff to get off the field. Shanahan said the team couldn’t tell if Evans broke a rib or injured his oblique, but he believes those questions will be answered tomorrow, indicating Evans will likely undergo imaging. He entered the game with a hip injury. Wagoner adds that LT Trent Williams (stinger) and LB Dre Greenlaw’s (quad) injuries “seemed less severe” than Evans’ injury.

McCaffrey and Williams were listed as DNP simply for rest, while Bosa had a rest/knee designation and Greenlaw had a rest/Achilles designation. This is notable as the 49ers have several key veterans who have dealt with injuries throughout their career and practice reps will be managed for these players, especially coming off a Week 1 in Australia. McCaffrey reportedly dealt with cramps in the 49ers’ Week 1 win over the Rams; though he is not injured, his experiences with Achilles tendinitis will certainly lend to rest days throughout the season. We expect the 49ers to continue to rest veterans in practice throughout the season in an effort to remain healthy.

Greenlaw played in just eight games with the Broncos last season, dealing with a quad injury, a hamstring injury and a one-game suspension. He totaled 25 solo tackles, five TFLs, one interception, two quarterback pressures and one sack despite the bumpy year. Prior to 2025, he spent his whole career playing for the 49ers.

The move clears $6 million in cap space. The 28-year-old is getting cut one season into a “three-year” deal. As was the case his final few campaigns in San Francisco, Greenlaw suffered through an injury-marred year in Denver, making just eight appearances. Greenlaw still made a play-making impact when on the field. It just wasn’t often enough for Sean Payton and company. Provided he can pass a physical right now, Greenlaw should still land guaranteed money for 2026.

Franklin-Myers boasts 39 quarterback pressures and eight sacks this season. The impactful interior defender’s return comes at the right time. The Broncos will also get LB Dre Greenlaw (hamstring) back in the lineup on Saturday.

The first-round bye gave Franklin-Myers an additional week to get healthy after he missed the Broncos’ Week 18 game. His full practice Tuesday is a good indication he will play in the Divisional Round against the Bills. LB Dre Greenlaw (hamstring) was also limited and could be nearing a return in the playoffs.

Franklin-Myers accounted for 39 quarterback pressures and eight sacks this season, though the Broncos should be okay without him. The Chargers are resting many of their impactful starters in an attempt to preserve good health for the postseason. The Broncos currently hold the AFC’s No. 1 playoff seed and can retain it with a win.