49ers head coach Kyle Shanahan said Christian McCaffrey (calf/Achilles) will not play in Week 2 and the team is considering placing him on injured reserve.
Per Shanahan, McCaffrey had his worst day in terms of pain and health following Thursday’s practice, prompting the change in tone from the team. Shanahan had previously told reporters that McCaffrey would not go on injured reserve. The superstar running back was even practicing in a limited capacity earlier this week. It’s a nightmare scenario for fantasy managers who were expecting to get McCaffrey back sooner rather than later. He will miss at least four games if placed on injured reserve. Jordan Mason will dominate the touches for San Francisco for the foreseeable future. Mason turned 28 carries into 147 yards and a touchdown in Week 1. He will rank as a high-end RB1 for as long as McCaffrey is on the sidelines.