49ers place Jake Tonges (knee) on injured reserve

No surprise here. Pierce shed his cast earlier this week, but there was also a report from the Athletic’s James Boyd that he “didn’t get the sense” Pierce was close to a return. Pelissero reports that Pierce isn’t expected to return to practice next week when he’s eligible. It’s difficult to justify holding Pierce in leagues without IR spots given the circumstances.

Mayfield didn’t practice this week, but according to Buccaneers HC Todd Bowles he threw on Monday and was pushing to play before his “thumb swelled up on him.” It seems like Mayfield is trending in the right direction and that he could return against the Panthers in Week 7 if the swelling is no longer an issue. Jalon Daniels is starting for Tampa Bay again in Week 6 against the Steelers.

While Hurts still has no timetable to return, the Eagles haven’t even discussed the possibility of placing him on injured reserve, according to Schefter. That could change as there’s still a possibility Hurts could wind up on injured reserve if that’s where the medical information leads them. Most blood clots are treated with anticoagulants (blood thinners), which would sideline Hurts for a minimum of six weeks, according to Schefter’s sources. The best-case scenario, according to Schefter, seems to be if the blood clot is minor enough that doctors could begin treatment with anti-inflammatories. Two team doctors that Schefter polled also speculated that the 28-year-old quarterback could miss six weeks. Tanner McKee is in line to start at least a few games while Hurts is out.

Brown returned to practice this week after going on injured reserve with a high-ankle sprain. While nothing is official yet, it’s a great sign that Rapoport is anticipating a return for the 29-year-old wide receiver in Week 6 against the Jets. Brown may not play a full complement of snaps in his first game back, but is still essentially a must-start for fantasy managers.

The Titans are 0-5 and have won only three games since Borgonzi joined the team prior to the 2025 season. Despite this, Nihill told ESPN’s Turron Davenport that he feels a “sense of stability” in the organization. Davenport, in turn, notes that the Titans “have fired a coach or general manager every year since 2022.” Nihill apologized to Titans fans, saying ownership and team executives feel “a sense of grief” about the endless losses, and “feel the sense of responsibility to deliver” for fans moving forward. We wish them luck.

Normally, social media posts don’t count for much. However, earlier today, Bears coach Ben Johnson said that the Bears should have more clarity on Williams’ status by the end of the day, after the medical team put Williams through “the final stress tests” in his return-to-play program. We are inferring that Williams’ social media post suggests he passed the final medical testing, though we have not officially received word that this is indeed the case. For now, we tentatively expect Williams to play on Sunday. He can be treated as a mid-to-low QB1.

Fowler is surprisingly saying the quiet part out loud here, though this has been the general consensus for fans and analysts for a while. Jacobs is scheduled to come off the NFL’s Commissioner Exempt list on Monday. The NFL is reportedly trying to get hold of the video, and Jacobs has sued to block its release. Fowler adds that the woman’s attorney said her client has not participated in the league’s investigation due to privacy concerns. If the video stays under wraps, Jacobs could be allowed to continue playing in the NFL.

Fowler reportedly spoke to “some people who are hopeful” that Hurts can avoid injured reserve. He described the situation as being “very much touch and go” and said Tanner McKee will “probably” start multiple games. The Eagles go on bye in Week 10, so if Hurts does land on injured reserve, the Eagles’ Week 11 game against the Steelers would be his earliest possible return.

Kirk’s inability to practice fully despite his lengthy injured reserve stint suggests he might need another week or two to get ready for an NFL game. Still, the 49ers don’t face the Commanders until Monday night. If active, he could end up warranting FLEX treatment with Mike Evans (ribs/Achilles) ailing.

Bosa is on the wrong side of questionable despite prior reports and coaching comments indicating he has a chance to face the Commanders on Monday night. For now, we expect Bosa to miss another week, though the extra day off could help him return.