49ers coach Kyle Shanahan said Brock Purdy will have a full practice Wednesday.
Purdy reported some back soreness Monday, but the team called him day to day after an MRI showed no structural damage.
Purdy went 22-of-30 for 292 yards and three touchdowns in Sunday’s loss to the Rams.
Tight end George Kittle (hamstring) is expected to return to limited work after missing the Week 3 game.
Left tackle Trent Williams (illness), linebacker Dee Winters (ankle) and wide receiver Deebo Samuel (calf) will not practice.