Kyle Monanga (hamstring) limited on Thursday

Slayton signed with the Colts less than a month ago but never suited up for the team on game day. The 29-year-old speedster was briefly considered as a candidate to replace Alec Pierce (foot), but he’s once again on the open market in search of work. A knee injury resulted in Slayton being scratched from Week 5’s matchup against the Steelers, so it’s possible he’ll have to prove he’s healthy before signing elsewhere this season.

Engram has not seen more than five targets in a game this season and has been held out of the end zone since Week 1, making him a difficult start in fantasy leagues of all sizes. He can safely remain on the bench in an enticing matchup against the Cardinals in Week 7.

Nix’s only incompletion when targeting Sutton resulted in the veteran receiver getting rocked over the middle of the field on a ball Nix led him directly into oncoming contact. Sutton vented his frustration by repeatedly pounding the ground following the hit, with it unclear whether it was due to the hit or the incompletion on third down on a night the Broncos struggled to move the football to the tune of only 168 yards of total offense. Fantasy managers likely aren’t utilizing Sutton as a weekly option, but will want to track his practice status ahead of a Week 7 meeting with the Cardinals if bye week fill-ins are required.

The fact that the 31 yards through the air led the team in receiving is a comment on the state of an offense that gained only 168 yards of total offense against the defending Super Bowl Champions. Even so, a relentlessly aggressive defense willed the team to victory behind a consistently positive game script, which allowed J.K. Dobbins to handily lead the backfield in opportunities. Harvey remains a matchup-dependent fantasy option best utilized in trailing game environments, which is unlikely to be the case when the Broncos face the struggling Cardinals in Week 7.

Dobbins found little room to run on a night the Broncos gained only 168 yards of total offense but handily led the backfield in opportunities in what was a consistently positive game script due to the dominance of their defense. Dobbins has now failed to eclipse a modest 50 yards on the ground in four of five appearances but might be useful as a bye week fill-in when the Broncos travel to Arizona to face the Cardinals in Week 7.

The Broncos managed just 168 yards of total offense on a night their defense carried them to victory in overtime. Nine of the Broncos’ 11 possessions, excluding the two kneel downs to end each half, ended in punts on drives that lasted five plays or fewer. Two second quarter touchdown drives had the Broncos playing with a lead for much of the game but they were otherwise unable to move the football with any consistency. An overtime interception by nickel corner Ja’Quan McMillian allowed for a game-winning, 53-yard field goal from kicker Will Lutz after the Broncos again failed to gain a first down. The win sends Denver to 4-2 while averaging only 18.7 points per game through six weeks. The team gets a scheduling gift with the Cardinals on deck in Week 7, although Nix cannot be treated as a starter-worthy fantasy asset outside of the deepest leagues.

Kupp’s 10 targets finished second on the team behind alpha Jaxon Smith-Njigba but were largely a product of 51 Sam Darnold pass attempts in game that had all the ingredients for increased pass volume, including an inability to run the football, negative game script, and overtime. It continues to appear as if Kupp’s fantasy-relevant days are far behind him, with the veteran best left on the waiver wire ahead of a Week 7 showdown against the Chiefs on deck.

Shaheed’s eight targets were a product of 51 Sam Darnold pass attempts in a game the Seahawks could not find any room to run on the ground. He lost a fumble on a fluke play in the second quarter in which he rolled over the tackling defender, only for the defender’s knee to knock the football loose before Shaheed’s rear end touched the playing surface. he would fumble a punt return in the fourth quarter but easily had time to regain control before the ball was in real trouble. Shaheed remains the third option through the air for an offense typically not seeing this level of volume, making him a touchdown-or-bust fantasy option, for the time being. That doesn’t change ahead of a Week 6 meeting with the Chiefs in Seattle.

Smith-Njigba overcame a sluggish first half to extend his stranglehold on the overall WR1 in fantasy circles with a dominant second half and overtime period. While the 51 pass attempts from Sam Darnold were highly uncharacteristic of this Seattle offense, a complete inability to run the football paired with a negative script to form the perfect environment for Smith-Njigba to set a season high in targets and receptions. Smith-Njigba has now gone over 100 yards in five of six appearances to start the 2026 regular season and is in a good spot to continue that dominance when the Seahawks host the Chiefs in Week 7, where he remains a top-tier WR1 in fantasy circles.

Holani split primary change of pace duties with recent practice squad call-up Velus Jones Jr, the latter of whom turned four carries into 20 yards while losing one yard on his lone reception. Both backs appear unlikely to return fantasy value as Zach Charbonnet nears a return from injured reserve.