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    Derwin James (hamstring) did not practice Wednesday.

    CB Donte Jackson (hamstring) also did not practice. Neither player played in Week 5 and both will need at least a limited practice before they can be considered questionable for Week 6 against the Chiefs.
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    Quentin Johnston (chest) was limited in Wednesday’s practice.

    Johnston, KeAndre Lambert-Smith (hamstring), Brenen Thompson (quad), and Marquez Valdes-Scantling (rib) were all limited Wednesday. Lambert-Smith currently has his practice window for return from IR open while the others are dealing with a varying level of ailments. Johnston is the best fantasy option out of this group, but he is only worth FLEX consideration in the deepest of leagues. With Ladd McConkey (foot) also limited, the Chargers have several “maybes” ahead of a Week 6 matchup against the Chiefs.
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    Joe Alt (neck) did not practice Wednesday.

    Alt missed Week 5 after not practicing last week and opens up Week 6 as a non-participant. Chargers coach Jim Harbaugh said Tuesday that Alt would visit a specialist for his neck injury. G Kayode Awosika (fibula) is also still sidelined. Justin Herbert’s offensive line looks like it will still be missing both players this week; the Chiefs’ defensive line will have a good day against the inexperienced depth that will start for the Chargers.
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    Chargers activated KeAndre Lambert-Smith’s (hamstring) 21-day practice window.

    The lanky downfield wide receiver could return to find himself seriously competing for a starting role. Lambert-Smith caught 5-of-12 targets for 51 yards and one touchdown as a rookie last year, yet drew praise from film analysts around the industry. The Chargers are desperate for offensive contributions. Lambert-Smith can be stashed in 14-team leagues, though his low odds of producing make him a tougher pickup in 12-team leagues.
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    Chargers coach Jim Harbaugh said he expects Ladd McConkey (foot) to practice on Wednesday.

    We, in turn, expect McConkey to be listed as a limited participant. An update will be provided if he practices in full. The Chargers’ No. 1 wide receiver was an emergency active last week, goose-egging in the box score. His early-week return to practice puts him on track to play in Week 6 against the Chiefs, but it would be great to see him practice in full by the end of the week.
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    Chargers signed QB Jake Browning to the practice squad.

    With Trey Lance hitting injured reserve, the Chargers worked out multiple quarterbacks Tuesday, eventually signing Browning. A former backup to Joe Burrow, Browning lost the Buccaneers’ backup job to Jalon Daniels this offseason. He now joins a Chargers team keen on adding some depth behind Justin Herbert with Lance out and DJ Uiagalelei on the 53-man roster.
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    Chargers coach Jim Harbaugh said OT Joe Alt (neck) will see a specialist.

    Last week’s offensive line in front of Justin Herbert featured four rookies and Cole Strange. It doesn’t look like it’s getting much better in Week 6.
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    Chargers coach Jim Harbaugh said Tre’ Harris (hamstring) is “more of a week-to-week [thing].”

    Harris will probably have a real chance to play in Week 8, after the Chargers’ Week 7 bye. He thudded to a 16-yard outing in his big chance last week with Quentin Johnston and Ladd McConkey out and doesn’t necessarily need to be rostered if you’re in a bye week crunch.
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    Chargers coach Jim Harbaugh said Quentin Johnston (chest) will “probably be limited this week like last for the practice.”

    “We’ll see where he’s at the end of the week,” Harbaugh added. Johnston practiced on both Thursday and Friday so he likely has the best chance of being active among Los Angeles’ main three wideouts. Unfortunately this passing game is in rough shape, and even a higher volume, healthy load probably wouldn’t get Johnston above the FLEX line.
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    Chargers coach Jim Harbaugh said it’s “possible” that Ladd McConkey (foot) is “working back in this week.”

    McConkey was active last week but an emergency-only player and played zero snaps. With the Chargers having a Week 7 bye, we’d be surprised if they pushed McConkey to play unless they really needed him. Unfortunately, since he was already active last week, we know that they may really need him. His status is up in the air ahead of Week 6.

Team Highlights

Which NFL teams are done, and who still has hope?
Not So Fast's Paul Pabst and Andrew Perloff decide which struggling NFL teams are officially “done, done” heading into Week 6, including the Chargers, Dolphins and Saints, while explaining why the Texans still have hope.