Staying up to date on NFL injury news is of the utmost importance for fantasy football success. The article below tracks all fantasy-relevant players currently listed on their team’s injury report and provides fantasy managers with actionable recommendations as new information rolls in.
Check back for updates from Tuesday through Saturday.
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**UPDATED AS OF WEDNESDAY, SEPTEMBER 30 AT 8:52 PM ET**
🏈 AFC East
◆ Buffalo Bills
DJ Moore - WR (shoulder)
Moore made it through Week 3 without aggravating his AC joint sprain. He was limited at Week 4’s first practice.
Impact: Minimal. Moore is a WR2 against the Patriots, who could be without cornerback Christian Gonzalez (shoulder.
◆ Miami Dolphins
De’Von Achane - RB (knee)
Achane suffered a torn ACL in the team’s Week 3 loss to the Chiefs, ending his season.
Impact: Achane’s unfortunate season-ending injury creates opportunity for Ollie Gordon and Jaylen Wright, both of whom are likely to be amongst the top waiver wire targets heading into Week 4. Even so, opportunity does not always translate to fantasy production, particularly when that opportunity is attached to the lowest-scoring offense in the league through three weeks. The timing of the injury makes it likely that Achane is able to fully recover before the start of the 2027 regular season.
Jaylen Wright - RB (foot)
Wright missed the team’s Week 3 loss to the Chiefs, but said he was “very close” to playing and resumed practicing in Week 4.
Impact: Wright is worth stashing, though he might not be worth starting against the Vikings this week. He offers more explosive upside than running back Ollie Gordon. This might end up being a fantasy-unfriendly situation.
Caleb Douglas - WR (ankle)
Douglas missed the team’s Week 3 loss to the Chiefs due to an ankle injury. He remains sidelined the following Wednesday.
Impact: Douglas continues to demonstrate splash play potential for one of the youngest offenses in the league and could return to streamer status once healthy, considering quarterback Malik Willis’ league-leading downfield throw rate.
Chris Bell - WR (knee)
Bell was limited on Wednesday.
Impact: Bell posted a career-best 4/67 receiving line last week. He is a WR4/FLEX against the Vikings in Week 4.
◆ New England Patriots
Drake Maye - QB (right shoulder)
Maye is practicing fully this week, albeit with a new and somewhat concerning injury in his throwing shoulder.
Impact: He is a shaky QB2 against the Bills.
A.J. Brown - WR (ankle)
The Patriots placed Brown on injured reserve with a high-ankle sprain.
Impact: Brown was diagnosed with the dreaded high-ankle sprain and will now be forced to miss the next four games while on injured reserve, with the soonest he can return being in Week 6 when the Patriots host the Jets. Reports surfaced Monday stating that Brown will not require surgery. Mack Hollins stands to benefit in snap rate and route participation rate in his absence, although it was slot-man DeMario Douglas who led the team in route rate in their Week 1 loss to the Seahawks. There is a small possibility second-year receiver Kyle Williams is allowed to grow into the offense as a deep threat with a long week of practice before the Patriots take the field following their opening day loss to the Seahawks on Wednesday.
Eli Raridon - TE (thigh)
Raridon injured his thigh in Week 2 and missed Week 3 against the Jaguars. He resumed practicing in a limited capacity in Week 4.
Impact: Starting tight end Hunter Henry would get a slight target share boost if Raridon cannot play.
◆ New York Jets
Breece Hall - RB (quadriceps)
Hall suffered a quadriceps injury in the team’s Week 3 loss to the Lions. Head coach Aaron Glenn labeled the talented running back week-to-week Monday.
Impact: Braelon Allen is in line to handle workhorse usage for as long as Hall remains sidelined, making him the top waiver priority entering Week 4.
Omar Cooper - WR (ankle)
Cooper is considered week-to-week after suffering a high-ankle sprain in Week 1. The team placed him on injured reserve Saturday.
Impact: Cooper’s absence could afford rookie tight end Kenyon Sadiq an opportunity to establish himself as a reliable contributor.
Adonai Mitchell - WR (finger)
Mitchell reportedly injured his finger in practice Thursday and was limited Friday. He did not play in Week 3 and remained sidelined the following Wednesday.
Impact: Garrett Wilson is in line to see all the volume he can handle for as long as Mitchell remains sidelined, while rookie tight end Kenyon Sadiq enters the TE1 range after a true coming-out party in Mitchell and Taylor’s absence in Week 3.
Mason Taylor - TE (thumb)
Taylor is reportedly considered week-to-week after suffering a thumb injury, though head coach Aaron Glenn’s comments cloud Taylor’s outlook. He did not play in Week 3 and remains sidelined in Week 4.
Impact: The injury should increase rookie tight end Kenyon Sadiq‘s usage. He is a top priority waiver add in all formats.
Kenyon Sadiq - TE (back)
Sadiq was reportedly limited on Wednesday.
Impact: Keep an eye on this one. Sadiq is a shoo-in TE1 if active.
🏈 AFC North
◆ Baltimore Ravens
Lamar Jackson - QB (back)
Jackson was limited on Wednesday.
Impact: Jackson is on track to play, warranting fantasy football QB1 treatment, though his practice participation is worth tracking.
Zay Flowers - WR (hamstring)
Flowers was limited to begin Week 4.
Impact: The Ravens have handled Flowers’ hamstring recurrence effectively. He should handle a larger snap share this week.
Mark Andrews - TE (hand)
Andrews is practicing in full for Week 4 against the Titans.
Impact: Andrews is a TE2 this week.
Ja’Kobi Lane - WR (wrist)
Lane suffered a fractured wrist in the team’s Week 1 win over the Colts. He was placed on injured reserve after undergoing surgery.
Impact: The popular breakout candidate caught a touchdown that was called back due to a penalty before departing with a fractured wrist in Week 1, and will now miss significant time. Rashod Bateman ran a route on almost every Lamar Jackson dropback in Week 1 but failed to catch his lone target. It remains more likely that Zay Flowers, if healthy, and Mark Andrews continue to be the points of emphasis through the air. Keep an eye on rookie wide receiver Elijah Sarratt.
◆ Cincinnati Bengals
Andrei Iosivas - WR (thumb)
The Bengals placed Iosivas on injured reserve in Week 3.
Impact: Wide receivers Colbie Young and Dohnte Meyers will duke it out for the No. 3 wide receiver role for at least the next four weeks. Meyers can be added in 14-team leagues, though his upside is questionable.
◆ Cleveland Browns
Dylan Sampson - RB (knee)
Sampson is expected to miss ‘significant time’ after suffering a knee injury in the team’s Week 1 loss to the Jaguars. He was placed on injured reserve in Week 2.
Impact: Veteran journeyman Reheim Sanders stepped into the vacated change-of-pace and passing-down role, which is noteworthy considering it wasn’t lead back Quinshon Judkins who saw his role grow. This backfield appears as close to a full stay-away as possible in fantasy circles, at least for as long as Deshaun Watson remains the starter under center.
◆ Pittsburgh Steelers
Rico Dowdle - RB (toe)
Dowdle did not play in Week 3 and has been ruled out for Week 4 against the Browns.
Impact: Jaylen Warren handled a true workhorse role in Dowdle’s absence in Week 3 and is likely to do so again in Week 4. Warren is a volume-backed RB1 for as long as Dowdle remains sidelined.
🏈 AFC South
◆ Houston Texans
Nico Collins - WR (hamstring)
Collins did not play in Week 3 but the team is “hopeful” he will return for Week 4. He resumed practicing in a limited capacity to begin the week.
Impact: Collins could potentially make his return from a two-game absence when the Texans take on the Cowboys in Week 4, although his snaps could be monitored considering the nature of his injury and his lengthy history with soft tissue issues.
Tank Dell - WR (knee)
Dell will begin the season on injured reserve.
Impact: Dell will miss the first four games of the regular season, at minimum. Expect Jaylin Noel to serve as the primary slot receiver while newcomer Kayshon Boutte starts on the perimeter opposite Nico Collins, for the time being.
Jayden Higgins - WR (knee)
Higgins saw his 2026 season taken from him due to a torn ACL suffered in camp.
Impact: It’s a massive blow to a Texans team that was counting on Higgins taking another step forward in his Sophomore campaign. The team traded for Kayshon Boutte in the wake of the injury.
◆ Indianapolis Colts
Alec Pierce - WR (heel)
Pierce aggravated the injury that required offseason surgery in Week 2. The Colts placed him on injured reserve in Week 3. He will attempt to avoid surgery by rehabbing his injured heel.
Impact: Josh Downs should serve as the primary option through the air for as long as Pierce remains sidelined. The team signed veteran field-stretcher Darius Slayton in the wake of Pierce’s injury, although he is unlikely to return weekly fantasy production.
◆ Jacksonville Jaguars
The Jaguars emerged from their Week 3 win over the Patriots absent any fantasy-relevant injuries.
◆ Tennessee Titans
Tony Pollard - RB (ankle)
See below.
Impact: See below.
Tyjae Spears - RB (ankle)
The Titans held Pollard and Spears out on Wednesday. The ineffective duo played through these injuries last week and head coach Robert Saleh said neither injury worries him.
Impact: Pollard is an RB3. Spears does not need to be rostered.
🏈 AFC West
◆ Denver Broncos
J.K. Dobbins - RB (hip)
Dobbins is practicing in full for Week 4 against the 49ers.
Impact: None. The veteran back is used to playing through injuries.
Jaylen Waddle - WR (foot)
Waddle was seen wearing a boot on his right foot post-game, but he is practicing in full for Week 4 against the 49ers.
Impact: Waddle should be good to go this week. He is a WR2.
Jonah Coleman - RB (ankle)
The team shocked fantasy managers Saturday, sending him to short-term injured reserve. He will be eligible to return in mid-October.
Impact: Coleman was initially viewed as the potential Week 3 starter, given Harvey and Dobbins’ ailments. Dobbins and Harvey will revert to a backfield tandem in the rookie’s absence.
Marvim Mims - WR (foot)
Mims was ruled out for Week 2 on Saturday, but resumed practicing to begin Week 3. He did not play in Week 3, but is practicing in full for Week 4.
Impact: The boom-bust wide receiver remains a frustratingly volatile player. He is not worth rostering in 12-team leagues.
◆ Kansas City Chiefs
The Chiefs emerged from their Week 3 win over the Dolphins absent any fantasy-relevant injuries.
◆ Las Vegas Raiders
Jack Bech - WR (forearm)
The Raiders placed Bech on injured reserve in Week 4.
Impact: Raiders wide receiver Tre Tucker could line up in the slot more often.
◆ Los Angeles Chargers
Ladd McConkey - WR (foot)
McConkey was limited by a new injury on Wednesday.
Impact: On the plus side, the Chargers’ No. 1 wide receiver is no longer listed with a ribs injury. The new issue is concerning. It is unclear when it occurred. Monitor this closely. Chargers wide receiver Tre’ Harris has outplayed wide receiver Quentin Johnston thus far. Harris would likely be the de facto top target earner if McConkey misses time.
Keaton Mitchell - RB (ankle)
Mitchell was seen wearing a boot on his left foot after practice. He was officially limited, which could indicate he suffered an ankle injury in practice.
Impact: Mitchell scored a red zone touchdown last week. Removing him from the lineup would boost running back Omarion Hampton‘s outlook.
Brenen Thompson - WR (hip)
Thompson remains sidelined in Week 4.
Impact: The Chargers’ veteran wide receiver trio has 11 personnel locked up.
Charlie Kolar - TE (forearm)
The team intended to place Kolar on injured reserve, but his prognosis changed during surgery.
Impact: The Chargers’ receiving specialist tight end Oronde Gadsden is the clear-cut starter in the short term. Gadsden flopped in Week 3 and can only be viewed as a boom-bust TE1/2.
David Njoku - TE (fibula)
Njoku is looking at an extended absence after being carted from the field in the team’s Week 2 loss to the Raiders. The Chargers placed him on injured reserve in Week 3.
Impact: See above.
🏈 NFC East
◆ Dallas Cowboys
Malik Davis - RB (hip)
Davis was placed on injured reserve and will miss the remainder of the 2026 season.
Impact: The Cowboys released both Jaydon Blue and Phil Mafah at roster cuts and now have only Emari Demercado on the active roster behind starter Javonte Williams. Expect Israel Abanikanda to be elevated to the active roster from the practice squad for Week 2, while Williams appears likely to see all the work he can handle against the Commanders. Williams is a locked-in RB1 in Week 2.
◆ New York Giants
Jaxson Dart - QB (knee)
Dart injured his MCL, PCL and meniscus on the team’s first possession of Monday Night Football against the Rams. He will undergo surgery to address the MCL and meniscus and miss the rest of the regular season. Giants head coach John Harbaugh said it is possible for Dart to return in the postseason, although this is unlikely.
Impact: Backup Jameis Winston was largely unable to sustain drives following Dart’s departure. Dart’s absence has an adverse effect on all skill position players in New York, most notably Malik Nabers, Isaiah Likely, and Cam Skattebo. We’ll know more regarding Dart’s expected timeline later this week.
Malik Nabers - WR (shoulder)
Nabers briefly departed the team’s Week 2 loss to the Rams with a shoulder injury, telling reporters post-game that it was a dislocation. He was limited on Wednesday and removed from the injury report Friday.
Impact: Nabers has had shoulder issues dating back to his time in college, with the most recent scare likely a result of his choice not to address the issue via offseason surgery during the same time he had his ACL reconstructed and meniscus repaired. Time will tell if this becomes something more serious. Fantasy managers will likely be forced to continue to start Nabers, even with the recent injury concerns and with Winston under center. That doesn’t mean it’ll feel great.
◆ Philadelphia Eagles
DeVonta Smith - WR (hamstring)
Smith did not practice on Wednesday after playing through this injury in Week 3.
Impact: Smith’s hamstring was an issue in training camp. He evidently experienced a recurrence last week, yet still posted a 6/65 receiving line. As long as he remains setback-free, he is a high-end WR2.
Dallas Goedert - TE (knee)
Goedert reportedly suffered a sprained MCL in the team’s Week 2 win over the Titans. he is expected to miss multiple weeks.
Impact: With both Goedert and Stowers now out, the team signed veteran tight end Zach Ertz Monday. Ertz is likely to serve as the primary pass-catching option at the position, although volume appears more likely to concentrate on receivers DeVonta Smith and Dontayvion Wicks.
Eli Stowers - TE (hamstring/quad)
The Eagles placed Stowers on injured reserve.
Impact: Stowers appears unlikely to have a meaningful role in the offense during his rookie season.
◆ Washington Commanders
Chig Okonkwo - TE (hamstring)
Okonkwo was unable to finish the team’s Week 1 loss to the Eagles and was unable to play in Week 2. He was limited to begin Week 3 but was ruled out Friday. He was limited at Week 4’s first practice.
Impact: Okonkwo’s absence could lead to additional 11-personnel, which raises the weekly floor and ceiling of talented rookie wide receiver Antonio Williams. Williams remains a worthwhile hold entering Week 3.
Jayden Daniels - QB (elbow)
Daniels suffered a dislocated elbow in Week 2, the same injury he suffered a season ago. ESPN’s Adam Schefter said Monday that it “sounds like” Daniels will eventually need surgery but is putting it off until after the season to compete in 2026. He was limited on Wednesday.
Impact: Marcus Mariota will remain the starter under center for as long as Daniels is sidelined. Managers in a bind at the position can add Mariota and hold him for easier starts against the Colts and Giants in the coming weeks.
Rachaad White - RB (shoulder)
The Commanders signed free agent running back Austin Ekeler this week, which is a bad sign for White’s availability. He is reportedly receiving treatment for the injury.
Impact: Depending on Ekeler’s readiness, starting running back Jacory Croskey-Merritt could take on more receiving work.
🏈 NFC North
◆ Chicago Bears
Caleb Williams - QB (hamstring)
Williams suffered a Grade 2 hamstring strain in the team’s Week 2 loss to the Vikings. Head coach Ben Johnson labeled him week-to-week on Monday. He was ruled out for Monday Night Football in Week 3 on Saturday. He remains sidelined early in Week 4.
Impact: Case Keenum led the Bears to victory over the Eagles on Monday Night Football, with head coach Ben Johnson saying “we’ll see how it plays out” when asked about the starter moving forward.
◆ Detroit Lions
Isiah Pacheco - RB (back)
Pacheco was placed on injured reserve to start the season. General Manager Brad Holmes said he “hopes Pacheco returns this season.”
Impact: Well, that doesn’t sound great. There appears to be something more insidious going on with Pacheco’s back than initially thought. Lions coach Dan Campbell said running backs Jacob Saylors and Sione Vaki could split touches behind Jahmyr Gibbs. Saylors appears to be the first player up. Gibbs handled an absurd 34 opportunities, of 37 total running back opportunities, in the team’s Week 1, overtime win over the Saints
◆ Green Bay Packers
Josh Jacobs - RB (commissioner exempt list)
Jacobs was placed on the commissioner exempt list amidst troubling domestic violence allegations. His initial court date was recently moved up from November to September 10. ESPN’s Jeremy Fowler reports Jacobs “could be looking at a 4-6 game suspension” after being activated from the exempt list.
Impact: The commissioner exempt list brings a wide range of outcomes regarding how many games we expect Jacobs to miss this season. That said, the fact that his initial court appearance was moved up near the start of the regular season could allow the league additional motivation to levy a suspension, pending the outcome of his appearance. Either way, don’t expect Jacobs on the field any time soon, leaving MarShawn Lloyd as the lead back in the interim.
Jayden Reed - WR (neck)
Reed suffered a scary-looking neck injury that required stabilization in the team’s Week 2 win over the Jets. Packers head coach Matt LaFleur said on Tuesday that it is “way too early” to determine whether Reed will play again in 2026. That said, he was not placed on injured reserve ahead of their Week 3 contest. He will reportedly undergo surgery.
Impact: Beyond the football implications, it is good to hear Reed avoided any life-altering injuries in Week 2. Skyy Moore and Bo Melton are likely to soak up additional snaps, although volume is most likely to concentrate on Christian Watson, Matthew Golden, and Tucker Kraft.
◆ Minnesota Vikings
Justin Jefferson - WR (ankle)
Jefferson suffered an ankle injury in the team’s Week 3 win over the Buccaneers. He is day-to-day and did not practice on Wednesday.
Impact: NFL Network’s Ian Rapoport reported Monday that the team received good news on Jefferson’s injury and it wasn’t “anything long-term,” with the hope that he can play in Week 4 against the Dolphins. That said, there is the potential for the team to hold him out as a precaution considering the level of competition. Jordan Addison would enter the upside WR2 range, should Jefferson miss.
Jordan Mason - RB (thumb)
The Vikings placed Mason on injured reserve in Week 2.
Impact: The Vikings are on bye in Week 6, so Mason will be eligible to return in Week 7. Starting running back Aaron Jones gets a deserved projections boost with Mason sidelined. Veteran RB DeeJay Dallas operated as the RB3. Rookie RB Demond Claiborne can be stashed on benches.
👉 Don’t forget: Check out the Rotoworld player news feed for all the latest news, notes, and transactions around the league.
🏈 NFC South
◆ Atlanta Falcons
The Falcons emerged from their Week 3 win over the Packers absent any fantasy-relevant injuries.
◆ Carolina Panthers
Jalen Coker - WR (quadricep)
Coker suffered a quad injury in Week 3 that forced him to depart the game. He was unable to practice on Wednesday to begin the week.
Impact: NFL Network’s Ian Rapoport reported Monday that Coker is considered questionable to play in Week 4 against the Lions. Fantasy managers will have to track his practice participation closely in the coming days. Second-year alpha Tetairoa McMillan would vault into the WR1 tier against the Lions, should Coker be unable to play. Panthers wide receiver Xavier Legette (knee) is week-to-week.
Bryce Young - QB (knee)
Young is practicing fully in Week 4 after undergoing imaging earlier this week.
Impact: Young took a cleat to the knee in Week 3, but he is good to go. He can be treated as a low-end QB1 against the Lions.
Jonathan Brooks - RB (groin)
Brooks aggravated the groin injury that forced him to miss the end of camp. The Panthers placed him on injured reserve in Week 3. He is expected to undergo core muscle surgery.
Impact: Chuba Hubbard enters the volume-driven RB1 discussion in Brooks’ absence.
◆ New Orleans Saints
Travis Etienne - RB (hamstring)
Etienne aggravated his hamstring injury in the team’s Week 3 loss to the Raiders. Head coach Kellen Moore said Monday that he expects Etienne to “miss some time.”
Impact: Alvin Kamara and Kendre Miller appear likely to split the load in Etienne’s absence, neither of whom is overly enticing in fantasy circles in what is expected to be a shared workload.
Jordyn Tyson - WR (hamstring)
Tyson begins the regular season on injured reserve. He will miss the first four games of the season, at minimum.
Impact: Devaughn Vele should begin the season in the starting lineup opposite Chris Olave, with both players routinely used in the slot. Olave’s weekly range of outcomes rivals almost any receiver in the league for as long as Tyson remains out, while tight end Juwan Johnson should return weekly TE1 finishes.
◆ Tampa Bay Buccaneers
Jalen McMillan - WR (knee)
McMillan suffered a sprained PCL in his first game action of the season in Week 3. The team placed him on injured reserve Monday, with an expected absence of 6-8 weeks.
Impact: Not much change considering he made his season debut in Week 3, although rookie Ted Hurst should remain in the starting lineup.
Baker Mayfield - QB (thumb)
Mayfield suffered a dislocated thumb in the team’s Week 3 loss to the Vikings.
Impact: Follow-up testing revealed the ligaments to be intact, but head coach Todd Bowles relayed Monday that Mayfield is expected to miss “at least three weeks.” The team did not place him on injured reserve Monday. Undrafted free agent rookie Jalon Daniels is in line to start in Mayfield’s absence. Daniels went undrafted for a reason, the primary of which was his inconsistencies as a passer. Consider it a significant downgrade for Emeka Egbuka, Chris Godwin, Ted Hurst, and Cade Otton.
Bucky Irving - RB (glute)
Irving missed time in the fourth quarter in Week 3. He was limited the following Wednesday.
Impact: Irving should be startable as an RB2 against the Packers, but his participation level is worth tracking this week.
Chris Godwin - WR (ankle)
Godwin did not practice on Wednesday.
Impact: Godwin is underperforming, hurt and is now forced to catch passes thrown by an undrafted free agent rookie quarterback. He cannot be trusted as a WR3/FLEX starter.
🏈 NFC West
◆ Arizona Cardinals
The Cardinals emerged from their Week 3 loss to the 49ers absent any fantasy-relevant injuries.
◆ Los Angeles Rams
Puka Nacua - WR (groin)
Nacua did not play the previous two weeks. On Wednesday, head coach Sean McVay said he expects Nacua to play in Week 4 against the Eagles.
Impact: Veteran Davante Adams set a career high in receiving yards in consecutive games in the absence of Nacua. Adams would remain a top-tier WR1 should Nacua miss more time. If active, Nacua will carry re-injury risk, but he must be started as an elite WR1.
Terrance Ferguson - TE (ankle)
Ferguson aggravated an ankle injury in the team’s Week 3 loss to the Broncos. Head coach Sean McVay said Monday that Ferguson is likely to miss Week 4. He did not practice on Wednesday.
Impact: Colby Parkinson also suffered an injury in Week 3, which left veteran Tyler Higbee as the primary pass-catching option at the position. Higbee is a borderline TE1 after going 8-62-1 against the Broncos, should both Parkinson and Ferguson miss Week 4.
Colby Parkinson - TE (shoulder)
Parkinson suffered an AC joint sprain in the team’s Week 3 loss to the Broncos.
Impact: See above.
◆ San Francisco 49ers
Demarcus Robinson - WR (ankle)
Robinson suffered a high-ankle sprain in the team’s Week 2 win over the Dolphins. He will miss significant time.
Impact: Reports suggest Jacob Cowing will be leaned on to fill the void left behind by the injuries to Robinson and De’Zhaun Stribling. Expect Mike Evans, assuming health, Christian McCaffrey, and George Kittle to soak up additional volume.
Mike Evans - WR (ribs)
Evans was unable to finish the team’s Week 3 win over the Cardinals with a ribs injury. That now makes consecutive games in which Evans was unable to finish due to unrelated injuries. He did not practice on Wednesday.
Impact: It sounds as if Evans’ injury is not overly serious, although fantasy managers will want to track his status closely this week. He is a WR2 if active. Should Evans miss Week 4, volume will be further concentrated on Christian McCaffrey, George Kittle, and Deebo Samuel.
De’Zhaun Stribling - WR (ankle)
Stribling suffered an ankle injury in the team’s Week 1 win over the Rams. The 49ers placed him on injured reserve in Week 2 after he underwent surgery to repair a deltoid ligament tear. He is expected to return in 10 weeks.
Impact: The Athletic’s Matt Barrows believes Demarcus Robinson will be the primary beneficiary.
Ricky Pearsall - WR (knee)
Pearsall was placed on season-ending injured reserve.
Impact: Pearsall will miss the entirety of the 2026 season.
KhaDarel Hodge - RB (knee)
Hodge did not practice on Wednesday.
Impact: Hodge is not fantasy-relevant on his own, but his potential absence would further reduce the target competition for active 49ers.
◆ Seattle Seahawks
Zach Charbonnet - RB (knee)
Charbonnet will begin the season on the physically unable to perform list, although the team remains optimistic he will be able to beat his initial recovery timeline. Head coach Mike Macdonald said the team could activate his 21-day practice window in Week 4.
Impact: Rookie Jadarian Price has not yet carved out a clear-cut lead rushing role. Charbonnet could return to a sizable role if his body is ready for it.
Jadarian Price - RB (chest)
Price was limited on Wednesday.
Impact: Price played through the injury in Week 3, and should do so again this week.