The sixth overall pick in the 2017 NBA Draft, Isaac’s career has been limited due to injuries. He’s exceeded 60 games played twice in nine seasons and missed all of the 2020-21 and 2021-22 seasons after suffering a torn left ACL in the Orlando bubble in the summer of 2020. There was hope that Isaac would return at some point during the 2021-22 season, but his knee did not respond as doctors had hoped. In 2025-26, Isaac appeared in 52 games, averaging 10.0 minutes before a knee injury ended his season in early March. Given the injury history, he’s likely to take on a limited role wherever he lands.