Staying up to date on NFL injury news is of the utmost importance for fantasy football success. The article below tracks all fantasy-relevant players currently listed on their team’s injury report and provides fantasy managers with actionable recommendations as new information rolls in.
Check back for updates from Tuesday through Saturday.
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**UPDATED AS OF SATURDAY, OCTOBER 10 AT 3:30 PM ET**
🏈 AFC East
◆ Buffalo Bills
DJ Moore - WR (shoulder)
Moore aggravated his shoulder injury in Week 4 and was forced from the game, unable to return. He drew the questionable tag for Week 5 after first practicing Saturday.
Impact: Moore could be facing an absence after the second time injuring his shoulder. Head coach Joe Brady said Monday that he wants to get tight end Dalton Kincaid more involved in the offense, which would be easier with Moore off the field.
Joshua Palmer - WR (shoulder)
Palmer injured his shoulder in practice Friday and was ruled out for Week 5 Saturday.
Impact: Keon Coleman and Khalil Shakir find themselves alone atop the depth chart at wide receiver with Palmer out and Moore looking to be on the wrong side of questionable, while head coach Joe Brady confirmed that rookie Skylar Bell will be active for the first time in his career.
◆ Miami Dolphins
De’Von Achane - RB (knee)
Achane suffered a torn ACL in the team’s Week 3 loss to the Chiefs, ending his season.
Impact: Achane’s unfortunate season-ending injury creates opportunity for Ollie Gordon and Jaylen Wright, both of whom are likely to be amongst the top waiver wire targets heading into Week 4. Even so, opportunity does not always translate to fantasy production, particularly when that opportunity is attached to the lowest-scoring offense in the league through three weeks. The timing of the injury makes it likely that Achane is able to fully recover before the start of the 2027 regular season.
Caleb Douglas - WR (ankle)
Douglas missed the previous two games and head coach Jeff Hafley said Monday that the team is taking it “one day at a time” with the young receiver. He remains sidelined early in Week 5 and was ruled out Friday.
Impact: Douglas continues to demonstrate splash play potential for one of the youngest offenses in the league and could return to streamer status once healthy, considering quarterback Malik Willis’ league-leading downfield throw rate.
Chris Bell - WR (knee)
The Dolphins continue to manage Bell’s reps in practice. He was removed from the injury report Friday and will play in Week 5.
Impact: Bell is a worthwhile bench stash at this time.
◆ New England Patriots
Rhamondre Stevenson - RB (knee)
Stevenson injured his knee late in Week 4. He logged a limited practice to begin Week 5 before drawing the questionable tag.
Impact: He could end up playing the RB2 role behind TreVeyon Henderson if the knee injury is bothering him, but Stevenson’s early-week participation puts him on track to play.
Mack Hollins - WR (calf)
Hollins departed the team’s Week 4 win over the Bills with a calf injury and did not return. He did not practice on Wednesday before being ruled out Friday.
Impact: Veteran practice squad call-up Efton Chism saw the biggest increase in routes following Hollins’ departure, which was particularly interesting considering the team’s general lack of downfield abilities. Perhaps Kyle Williams could finally see additional time on the field.
A.J. Brown - WR (ankle)
The Patriots placed Brown on injured reserve with a high-ankle sprain.
Impact: Brown was diagnosed with the dreaded high-ankle sprain and will now be forced to miss the next four games while on injured reserve, with the soonest he can return being in Week 6 when the Patriots host the Jets. Reports surfaced Monday stating that Brown will not require surgery. Mack Hollins stands to benefit in snap rate and route participation rate in his absence, although it was slot-man DeMario Douglas who led the team in route rate in their Week 1 loss to the Seahawks. There is a small possibility second-year receiver Kyle Williams is allowed to grow into the offense as a deep threat with a long week of practice before the Patriots take the field following their opening day loss to the Seahawks on Wednesday.
◆ New York Jets
Breece Hall - RB (quadriceps)
Hall suffered a quadriceps injury in the team’s Week 3 loss to the Lions. Head coach Aaron Glenn labeled the talented running back week-to-week the following Monday, and reaffirmed the same status in Week 5. He was ruled out for Week 5 Friday.
Impact: Braelon Allen handled a true workhorse role in the absence of Hall in Week 4, with his box score suppressed by only 32 offensive plays run from scrimmage against the Bears (third fewest since the merger). Allen can be started as a volume-driven RB2 in Week 5.
Omar Cooper - WR (ankle)
Cooper is considered week-to-week after suffering a high-ankle sprain in Week 1. The team placed him on injured reserve Saturday.
Impact: Cooper’s absence could afford rookie tight end Kenyon Sadiq an opportunity to establish himself as a reliable contributor.
Adonai Mitchell - WR (finger)
Mitchell reportedly injured his finger in practice Thursday and was limited Friday. He was ruled out for Week 5 Friday.
Impact: Garrett Wilson is in line to see all the volume he can handle for as long as Mitchell remains sidelined, while rookie tight end Kenyon Sadiq enters the TE1 range.
Mason Taylor - TE (thumb)
Taylor is reportedly considered week-to-week after suffering a thumb injury, though head coach Aaron Glenn’s comments cloud Taylor’s outlook. He did not play in Week 3 and remained sidelined in Week 4. He is practicing in full for Week 5.
Impact: Taylor’s likely return could reduce rookie tight end Kenyon Sadiq‘s snap share, though Sadiq should remain involved after a productive Week 3.
🏈 AFC North
◆ Baltimore Ravens
Lamar Jackson - QB (ankle)
Jackson departed just before the half with an ankle injury and did not return in Week 4. He did not practice the following Wednesday and was ruled out for Week 5.
Impact: NFL Network’s Ian Rapoport reported Monday that the thought from the Ravens is that Jackson will miss a week or two, but has an “outside chance” of starting against the Falcons in Week 5. Although wide receiver Zay Flowers remains an elite fantasy option, his true ceiling inarguably takes a significant hit with Huntley under center. Even so, fantasy managers can continue to start him as a WR1. NFL Network’s Ian Rapoport reported that the team is now unsure if Jackson will play in Week 6 against the Browns.
Zay Flowers - WR (foot)
Flowers was limited on Wednesday before drawing the questionable tag for Week 5.
Impact: We do not know when this injury occurred. If it was an in-game issue and he is already practicing on Wednesday, he should be good to go. If it occurred in practice on Wednesday, he should be considered questionable to play. Stay tuned. Ravens wide receivers Rashod Bateman (shoulder) and Chris Moore (ankle) were limited to begin the week. Bateman would be tough to trust if Huntley starts and Flowers sits.
Durham Smythe - TE (Achilles)
Smythe suffered a torn Achilles in the team’s Week 4 win over the Titans. His season is done.
Impact: It was Matt Hibner who saw the largest increase in snaps following Smythe’s departure in Week 4, making it unlikely we see veteran Mark Andrews in a more robust role.
Ja’Kobi Lane - WR (wrist)
Lane suffered a fractured wrist in the team’s Week 1 win over the Colts. He was placed on injured reserve after undergoing surgery.
Impact: The popular breakout candidate caught a touchdown that was called back due to a penalty before departing with a fractured wrist in Week 1, and will now miss significant time. Rashod Bateman ran a route on almost every Lamar Jackson dropback in Week 1 but failed to catch his lone target. It remains more likely that Zay Flowers, if healthy, and Mark Andrews continue to be the points of emphasis through the air. Keep an eye on rookie wide receiver Elijah Sarratt.
◆ Cincinnati Bengals
Ja’Marr Chase - WR (concussion)
Chase was forced from the team’s Week 4 contest after a vicious facemask penalty. Head coach Zac Taylor confirmed Monday that Chase is in the league’s concussion protocol. He is listed as questionable for Week 5 after practicing in full Friday.
Impact: Former CFL standout Dohnte Meyers would be in line to serve as the primary wide receiver, should both miss Week 5, while tight end Mike Gesicki could be utilized more as a “big slot.”
Tee Higgins - WR (adductor/neck)
Higgins did not practice on Wednesday, despite head coach Zac Taylor indicating that he would. He upgraded to a full session Friday before drawing the questionable tag for Week 5.
Impact: Higgins departed the team’s Week 4 game with under five minutes left to play in the fourth quarter with an adductor injury. As mentioned above, Meyers would serve as the team’s top wide receiver if Chase and Higgins are sidelined.
Andrei Iosivas - WR (thumb)
The Bengals placed Iosivas on injured reserve in Week 3
Impact: Wide receivers Colbie Young and Dohnte Meyers will duke it out for the No. 3 wide receiver role for at least the next four weeks. Meyers can be added in 14-team leagues, though his upside is questionable.
◆ Cleveland Browns
Dylan Sampson - RB (knee)
Sampson is expected to miss ‘significant time’ after suffering a knee injury in the team’s Week 1 loss to the Jaguars. He was placed on injured reserve in Week 2.
Impact: Veteran journeyman Reheim Sanders stepped into the vacated change-of-pace and passing-down role, which is noteworthy considering it wasn’t lead back Quinshon Judkins who saw his role grow. This backfield appears as close to a full stay-away as possible in fantasy circles, at least for as long as Deshaun Watson remains the starter under center.
◆ Pittsburgh Steelers
Rico Dowdle - RB (toe)
Dowdle did not play in Week 3 and has been ruled out for Week 4 against the Browns. Head coach Mike Tomlin said Monday that the veteran back is “making progress” but would not speculate on his potential availability for Week 5. He was limited to begin the week and drew the questionable tag.
Impact: Jaylen Warren is a volume-backed RB1 for as long as Dowdle remains sidelined.
Michael Pittman - WR (foot)
Pittman was limited on Wednesday before being seen using a scooter in the locker room after practice. It was then revealed that Pittman aggravated his foot injury and will miss multiple weeks.
Impact: Pittman’s absence opens the door for Roman Wilson to operate as the WR2 behind DK Metcalf, while rookie Germie Bernard likely enters the starting lineup on the perimeter. Wilson has seen six targets in each game this season and profiles as the priority waiver addition.
🏈 AFC South
◆ Houston Texans
Tank Dell - WR (knee)
Dell began the season on injured reserve. Head coach DeMeco Ryans said Monday that the team would activate Dell’s 21-day practice window this week. He was limited on Wednesday but ruled out for Week 5 Friday.
Impact: Expect Jaylin Noel to serve as the primary slot receiver while newcomer Kayshon Boutte starts on the perimeter opposite Nico Collins, for the time being. Dell could work his way back into primary slot duties once healthy.
Jayden Higgins - WR (knee)
Higgins saw his 2026 season taken from him due to a torn ACL suffered in camp.
Impact: It’s a massive blow to a Texans team that was counting on Higgins taking another step forward in his Sophomore campaign. The team traded for Kayshon Boutte in the wake of the injury.
◆ Indianapolis Colts
Alec Pierce - WR (heel)
Pierce aggravated the injury that required offseason surgery in Week 2. The Colts placed him on injured reserve in Week 3. He will attempt to avoid surgery by rehabbing his injured heel.
Impact: Josh Downs should serve as the primary option through the air for as long as Pierce remains sidelined. The team signed veteran field-stretcher Darius Slayton in the wake of Pierce’s injury, although he is unlikely to return weekly fantasy production. Slayton (knee) was ruled out for Week 5 Friday.
Keenan Allen - WR (groin)
Allen injured his groin during a Week 4 practice and was unable to play on Sunday. He resumed practicing the following Wednesday. He drew the questionable tag for Week 5.
Impact: Josh Downs and tight end Tyler Warren will likely benefit if Allen is unable to play this week. Allen barely warrants FLEX consideration if active.
◆ Jacksonville Jaguars
The Jaguars emerged from their Week 4 win over the Bengals absent any fantasy-relevant injuries.
◆ Tennessee Titans
Tony Pollard - RB (foot)
Pollard played through an ankle injury over the last couple of weeks. It is unclear whether this injury is related. He did not practice on Wednesday. Pollard was removed from the injury report Friday and will play in Week 5.
Impact: Minimal. The Titans’ backfield is largely avoidable.
🏈 AFC West
◆ Denver Broncos
Pat Bryant - WR (ankle)
Bryant suffered an ankle injury in the team’s Week 4 loss to the 49ers and is reportedly expected to miss “a few weeks.” He was placed on injured reserve Friday.
Impact: Troy Franklin and Marvin Mims appear to be the next men up in Bryant’s absence, although the team could use a “sum of all parts” mentality to bridge his absence, considering historical trends. Alpha wide receiver Jaylen Waddle would be the primary beneficiary.
Jonah Coleman - RB (ankle)
The team shocked fantasy managers Saturday, sending him to short-term injured reserve. He will be eligible to return in mid-October.
Impact: Coleman was initially viewed as the potential Week 3 starter, given Harvey and Dobbins’ ailments. Dobbins and Harvey will revert to a backfield tandem in the rookie’s absence.
◆ Kansas City Chiefs
Rashee Rice - WR (hamstring)
Rice departed Week 4 with a hamstring injury and is reportedly looking at a several-week absence.
Impact: It was Jalen Royals who stepped into Rice’s role following the latter’s departure, although rookie Cyrus Allen would appear to be a better fit in the short term. The Chiefs are now without a viable deep threat following the devastating injury suffered by Tyquan Thornton, with reports surfacing that they have reached out to free agent Tyreek Hill. Stay tuned as this saga unfolds.
Tyquan Thornton - WR (ankle)
Thornton suffered a devastating ankle injury due to a hip-drop tackle in Week 4. He is reportedly set to undergo surgery within the week and will miss 12-16 weeks.
Impact: See above.
◆ Las Vegas Raiders
Brock Bowers - TE (knee)
Bowers was limited on Wednesday. The team removed him from the injury report Friday.
Impact: None.
Jalen Nailor - WR (concussion)
Nailor did not practice on Wednesday. He was ruled out for Week 5 Friday.
Impact: The Raiders’ wide receiver injuries have allowed wide receiver Cody White to be a surprisingly effective contributor.
Dont’e Thornton - WR (hamstring)
The Raiders activated Thornton’s 21-day practice window from injured reserve on Wednesday. Thornton says he is “ready” to play, although the team ruled him out for Week 5 Friday.
Impact: Thornton could carve out a role as a deep threat, once healthy, but can only be viewed as a dart throw.
Jack Bech - WR (forearm)
The Raiders placed Bech on injured reserve in Week 4.
Impact: Raiders wide receiver Tre Tucker could line up in the slot more often.
◆ Los Angeles Chargers
Ladd McConkey - WR (foot)
McConkey aggravated the foot injury suffered earlier in the season and is now labeled “day-to-day” by the team. Head coach Jim Harbaugh told reporters early on Wednesday that McConkey would be “at practice,” though he was ultimately listed as a non-participant. Harbaugh notably sparred with media members post-game. His commentary on McConkey’s return timeline could be unreliable. The team listed him as questionable for Week 5 on their final injury report.
Impact: Chargers wide receiver Tre’ Harris has outplayed wide receiver Quentin Johnston thus far, the latter of whom was ruled out for Week 5 with a chest injury. Harris would likely be the de facto top target earner if McConkey misses time.
Quentin Johnston - WR (chest)
See above.
Impact: See above.
Brenen Thompson - WR (hip)
Thompson remained sidelined in Week 4. He resumed practicing in Week 5.
Impact: See above.
Charlie Kolar - TE (forearm)
The team intended to place Kolar on injured reserve, but his prognosis changed during surgery. The team kept the door open for a potential return after listing him questionable for Week 5.
Impact: The Chargers’ receiving specialist tight end Oronde Gadsden is the clear-cut starter in the short term. Gadsden flopped in Week 3 and can only be viewed as a boom-bust TE2.
David Njoku - TE (fibula)
Njoku is looking at an extended absence after being carted from the field in the team’s Week 2 loss to the Raiders. The Chargers placed him on injured reserve in Week 3.
Impact: See above.
🏈 NFC East
◆ Dallas Cowboys
Malik Davis - RB (hip)
Davis was placed on injured reserve and will miss the remainder of the 2026 season.
Impact: The Cowboys released both Jaydon Blue and Phil Mafah at roster cuts and now have only Emari Demercado on the active roster behind starter Javonte Williams. Expect Israel Abanikanda to be elevated to the active roster from the practice squad for Week 2, while Williams appears likely to see all the work he can handle against the Commanders. Williams is a locked-in RB1 in Week 2.
CeeDee Lamb - WR (quad)
Lamb departed the team’s Week 5 loss to the Buccaneers in the fourth quarter with a quad injury. NFL Network’s Ian Rapoport reported the team does not believe the injury to be serious.
Impact: Regardless of the early reports, fantasy managers will want to keep a watchful eye on the level of participation of Lamb in the coming week. George Pickens would be in line to serve as the top option through the air if Lamb were to miss time, immediately vaulting into the WR1 discussion in fantasy circles.
◆ New York Giants
Malik Nabers - WR (knee)
Nabers is reportedly feeling “more sore than usual” and was unable to practice on Wednesday. He is reportedly “good to go” for Week 5.
Impact: Rookie wide receiver Malachi Fields can be stashed at this time.
Cam Skattebo - RB (shoulder)
Skattebo practiced in a limited capacity while sporting a red non-contact jersey on Wednesday. He was removed from the injury report Friday and will play against the Commanders in Week 5.
Impact: Veteran running back Najee Harris has been operating as his primary backup, though he missed practice on Wednesday due to a personal issue.
Isaiah Likely - TE (knee/groin)
Likely was limited after picking up two injuries in Week 4. He was removed from the injury report Friday and will play in Week 5.
Impact: None.
Jaxson Dart - QB (knee)
Dart injured his MCL, PCL and meniscus on the team’s first possession of Monday Night Football against the Rams. He will undergo surgery to address the MCL and meniscus and miss the rest of the regular season. Giants head coach John Harbaugh said it is possible for Dart to return in the postseason, although this is unlikely.
Impact: Backup Jameis Winston was largely unable to sustain drives following Dart’s departure. Dart’s absence has an adverse effect on all skill position players in New York, most notably Malik Nabers, Isaiah Likely, and Cam Skattebo. We’ll know more regarding Dart’s expected timeline later this week.
◆ Philadelphia Eagles
Saquon Barkley - RB (hamstring)
The veteran workhorse pulled up lame in the second quarter of Week 4 and is reportedly considered “week-to-week.” He did not practice on Wednesday and was ruled out for Week 5 Friday.
Impact: Primary backup Tank Bigsby also departed the team’s Week 4 loss to the Rams, leaving with a core muscle injury that requires surgery. He was placed on injured reserve Monday. Running back Will Shipley is the active roster incumbent, but Dameon Pierce was signed to the active roster this week and could challenge for the lead rushing role. Hopefully, incoming reports clarify their expected usage.
Tank Bigsby - RB (core)
See above.
Impact: See above.
DeVonta Smith - WR (hamstring)
Smith did not practice on Wednesday after playing through this injury in Week 3. He was ruled out for Week 4 and remained sidelined to begin Week 5. The team ruled him out for Week 5 Friday.
Impact: Smith’s hamstring was an issue in training camp. He evidently experienced a recurrence last week, yet still posted a 6/65 receiving line. The team will not be down to Dontayvion Wicks and rookie Makai Lemon as its top two pass catchers against the Rams. Neither is an overly exciting start in fantasy.
Dallas Goedert - TE (knee)
Goedert reportedly suffered a sprained MCL in the team’s Week 2 win over the Titans. He is expected to miss multiple weeks and was ruled out for Week 4. He resumed practicing in Week 5 and is not on the final injury report.
Impact: Goedert returns as the top option through the air in the absence of DeVonta Smith and Saquon Barkley. He is a TE1 against the Jaguars.
Eli Stowers - TE (hamstring/quad)
The Eagles placed Stowers on injured reserve.
Impact: Stowers appears unlikely to have a meaningful role in the offense during his rookie season.
◆ Washington Commanders
Terry McLaurin - WR (hamstring)
McLaurin remains sidelined in Week 5 after injuring his hamstring during a Week 4 practice. He is reportedly a true game-time decision for Week 5.
Impact: Rookie Antonio Williams should step into a more robust role. He possesses WR3 upside and could operate as the team’s No. 1 wide receiver. More below.
Stefon Diggs - WR (hamstring)
Diggs apparently injured his hamstring in Week 4 and remains sidelined to begin Week 5. He was ruled out for Week 5 Friday.
Impact: See above.
Jayden Daniels - QB (elbow)
Daniels suffered a dislocated elbow in Week 2, the same injury he suffered a season ago. ESPN’s Adam Schefter said Monday that it “sounds like” Daniels will eventually need surgery but is putting it off until after the season to compete in 2026. He is practicing in full and is reportedly “on track” to start in Week 5.
Impact: Marcus Mariota departed the team’s Week 4 loss in London with a sprained MCL, leaving Athan Kaliakmanis as the likely backup, for the time being. Mariota remains sidelined in Week 5.
Marcus Mariota - QB (knee)
See above.
Impact: See above.
Jacory Croskey-Merritt - RB (groin)
The Commanders’ run-centric starter was limited on Wednesday. He was removed from the injury report Friday and will play in Week 5.
Impact: He is on track to play, but remains touchdown-dependent.
Rachaad White - RB (shoulder)
White was ruled out for Week 4 on Friday and resumed practicing in a limited capacity the following Wednesday. The team removed his injury designation Friday. He will play against the Giants.
Impact: None.
Chig Okonkwo - TE (hamstring)
Okonkwo was limited on Wednesday but removed from the injury report Friday.
Impact: Wide receiver health pending, Okonkwo could warrant TE1 treatment.
Jaylin Lane - WR (ankle)
Lane suffered a dislocated ankle and fracture in Week 4 and is likely done for the season.
Impact: Minimal. Lane was primarily a special teams contributor.
🏈 NFC North
◆ Chicago Bears
Caleb Williams - QB (hamstring)
Williams suffered a Grade 2 hamstring strain in the team’s Week 2 loss to the Vikings. Head coach Ben Johnson labeled him week-to-week on Monday. The team listed him questionable for Week 5, with the caveat that Tyson Bagent is likely to start.
Impact: Tyson Bagent will reportedly draw another start in Week 5.
Kyle Monangai - RB (thumb/toe)
Head coach Ben Johnson labeled Monangai as “day-to-day” with a thumb injury suffered in Week 4. Johnson said Monangai’s thumb injury is not an “issue,” but did not address the toe injury. Monangai was sidelined on Wednesday before being ruled out for Week 5.
Impact: D’Andre Swift suddenly finds himself in one of the better spots for Week 5, with the backfield mostly to himself against a poor Packers defense. Fire him up in all formats as a top-tier RB1.
D’Andre Swift - RB (knee/hip)
Swift did not practice on Wednesday. He was removed from the injury report Friday and will play against the Packers.
Impact: Swift is a high-end RB1 against the Packers in the absence of Monangai.
◆ Detroit Lions
Isiah Pacheco - RB (back)
Pacheco was placed on injured reserve to start the season. General Manager Brad Holmes said he “hopes Pacheco returns this season.”
Impact: Well, that doesn’t sound great. There appears to be something more insidious going on with Pacheco’s back than initially thought. Lions coach Dan Campbell said running backs Jacob Saylors and Sione Vaki could split touches behind Jahmyr Gibbs. Saylors appears to be the first player up. Gibbs handled an absurd 34 opportunities, of 37 total running back opportunities, in the team’s Week 1, overtime win over the Saints
◆ Green Bay Packers
Josh Jacobs - RB (commissioner exempt list)
Jacobs was placed on the commissioner exempt list amidst troubling domestic violence allegations. His initial court date was recently moved up from November to September 10. ESPN’s Jeremy Fowler reports Jacobs “could be looking at a 4-6 game suspension” after being activated from the exempt list.
Impact: The commissioner exempt list brings a wide range of outcomes regarding how many games we expect Jacobs to miss this season. That said, the fact that his initial court appearance was moved up near the start of the regular season could allow the league additional motivation to levy a suspension, pending the outcome of his appearance. Either way, don’t expect Jacobs on the field any time soon, leaving MarShawn Lloyd as the lead back in the interim.
Jayden Reed - WR (neck)
Reed suffered a scary-looking neck injury that required stabilization in the team’s Week 2 win over the Jets. Packers head coach Matt LaFleur said on Tuesday that it is “way too early” to determine whether Reed will play again in 2026. That said, he was not placed on injured reserve ahead of their Week 3 contest. He will reportedly undergo surgery.
Impact: Beyond the football implications, it is good to hear Reed avoided any life-altering injuries in Week 2. Skyy Moore and Bo Melton are likely to soak up additional snaps, although volume is most likely to concentrate on Christian Watson, Matthew Golden, and Tucker Kraft.
Chris Brooks - RB (ankle)
Brooks suffered an ankle injury in the team’s Week 4 win over the Buccaneers and is reportedly undergoing further testing. He did not practice on Wednesday and was ruled out for Week 5 Friday.
Impact: Brooks had been the most consistent rusher in a timeshare situation. Kaleb Johnson lost another fumble in Week 4, leaving MarShawn Lloyd as the likely beneficiary for as long as Brooks remains sidelined, although that role carries little value for the team with the fewest rush attempts in the league through the first month of the season.
◆ Minnesota Vikings
Justin Jefferson - WR (ankle)
Jefferson suffered an ankle injury in the team’s Week 3 win over the Buccaneers. He did not play in Week 4. He told reporters that he plans to play in Week 5, though he has not yet been fully cleared. He was limited on Wednesday before being listed as questionable, although ESPN’s Jeremy Fowler reports Jefferson “plans to play” against the Saints.
Impact: See below.
Jordan Addison - WR (hamstring)
Addison did not practice on Wednesday due to “a little hamstring soreness.” He is listed as questionable for Week 5.
Impact: Tight end T.J. Hockenson took over as the team’s top target earner last week. He would benefit if Addison and/or Jefferson miss Week 5.
Jordan Mason - RB (thumb)
The Vikings placed Mason on injured reserve in Week 2.
Impact: The Vikings are on bye in Week 6, so Mason will be eligible to return in Week 7. Starting running back Aaron Jones gets a deserved projections boost with Mason sidelined. Veteran RB DeeJay Dallas operated as the RB3. Rookie RB Demond Claiborne can be stashed on benches.
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🏈 NFC South
◆ Atlanta Falcons
The Falcons emerged from their Week 4 win over the Saints absent any fantasy-relevant injuries.
◆ Carolina Panthers
Jalen Coker - WR (quadricep)
Coker suffered a quad injury in Week 3 that forced him to depart the game. He did not play in Week 4. The Panthers are on bye in Week 5.
Impact: The team’s Week 5 bye should afford Coker enough time to return after one missed game.
Jonathan Brooks - RB (groin)
Brooks aggravated the groin injury that forced him to miss the end of camp. The Panthers placed him on injured reserve in Week 3. He is expected to undergo core muscle surgery.
Impact: Chuba Hubbard enters the volume-driven RB1 discussion in Brooks’ absence.
◆ New Orleans Saints
Tyler Shough - QB (left hand)
Shough injured his non-throwing hand. He was limited on Wednesday but removed from the injury report Friday.
Impact: It will not impact his throwing ability.
Alvin Kamara - RB (back)
Kamara did not practice on Wednesday before being listed as questionable for Week 5.
Impact: Running back Kendre Miller is Kamara’s primary backup, though rookie running back CJ Donaldson has been involved off-and-on. Running back-needy managers can stash either player.
Travis Etienne - RB (hamstring)
Etienne aggravated his hamstring injury in the team’s Week 3 loss to the Raiders. Head coach Kellen Moore said Monday that he expects Etienne to “miss some time.”
Impact: Alvin Kamara and Kendre Miller appear likely to split the load in Etienne’s absence, neither of whom is overly enticing in fantasy circles in what is expected to be a shared workload.
Jordyn Tyson - WR (hamstring)
Tyson began the regular season on injured reserve.
Impact: Devaughn Vele should begin the season in the starting lineup opposite Chris Olave, with both players routinely used in the slot. Olave’s weekly range of outcomes rivals almost any receiver in the league for as long as Tyson remains out, while tight end Juwan Johnson should return weekly TE1 finishes.
◆ Tampa Bay Buccaneers
Jalen McMillan - WR (knee)
McMillan suffered a sprained PCL in his first game action of the season in Week 3. The team placed him on injured reserve Monday, with an expected absence of 6-8 weeks.
Impact: Not much change considering he made his season debut in Week 3, although rookie Ted Hurst should remain in the starting lineup.
Baker Mayfield - QB (thumb)
Mayfield suffered a dislocated thumb in the team’s Week 3 loss to the Vikings. He is expected to be sidelined for three-to-six weeks.
Impact: Undrafted free agent rookie Jalon Daniels will start in Mayfield’s absence. Daniels went undrafted for a reason, the primary of which was his inconsistencies as a passer. Consider it a significant downgrade for Emeka Egbuka, Chris Godwin, Ted Hurst, and Cade Otton.
🏈 NFC West
◆ Arizona Cardinals
Jeremiyah Love - RB (ankle)
Head coach Mike LaFleur said Love “tweaked his ankle” in Week 4. It is a new injury, not a recurrence. He was limited on Wednesday but removed from the injury report Friday.
Impact: Tyler Allgeier and Love both profile as RB3s, with Love playing downtrodden and hurt.
◆ Los Angeles Rams
Terrance Ferguson - TE (ankle)
Ferguson aggravated an ankle injury in the team’s Week 3 loss to the Broncos. Head coach Sean McVay said Monday that Ferguson is likely to miss Week 4. He did not practice on Wednesday and was sent to injured reserve Friday. He will miss the next four games, at minimum.
Impact: Colby Parkinson and Tyler Higbee should share primary tight end duties while Ferguson is absent.
Colby Parkinson - TE (shoulder)
Parkinson suffered an AC joint sprain in the team’s Week 3 loss to the Broncos. He did not play in Week 4 but was removed from the injury report Friday.
Impact: See above.
◆ San Francisco 49ers
Demarcus Robinson - WR (ankle)
Robinson suffered a high-ankle sprain in the team’s Week 2 win over the Dolphins. He will miss significant time.
Impact: Reports suggest Jacob Cowing will be leaned on to fill the void left behind by the injuries to Robinson and De’Zhaun Stribling. Expect Mike Evans, assuming health, Christian McCaffrey, and George Kittle to soak up additional volume.
Mike Evans - WR (ribs)
Evans was unable to finish the team’s Week 3 win over the Cardinals with a ribs injury. He played just 59 percent of the team’s offensive snaps in Week 4, yet caught five passes for 76 yards. He remains limited to begin Week 5 but was removed from the injury report Friday.
Impact: Evans avoided re-injury and can be treated as a WR2, as usual.
Kaelon Black - RB (illness)
Black was limited on Wednesday but removed from the injury report Friday.
Impact: None.
De’Zhaun Stribling - WR (ankle)
Stribling suffered an ankle injury in the team’s Week 1 win over the Rams. The 49ers placed him on injured reserve in Week 2 after he underwent surgery to repair a deltoid ligament tear. He is expected to return in 10 weeks.
Impact: The Athletic’s Matt Barrows believes Demarcus Robinson will be the primary beneficiary.
Ricky Pearsall - WR (knee)
Pearsall was placed on season-ending injured reserve.
Impact: Pearsall will miss the entirety of the 2026 season.
◆ Seattle Seahawks
Zach Charbonnet - RB (knee)
Charbonnet will begin the season on the physically unable to perform list, although the team remains optimistic he will be able to beat his initial recovery timeline. Head coach Mike Macdonald said the team could activate his 21-day practice window in Week 4. That said, he has already been ruled out for Week 5.
Impact: Charbonnet could return to a sizable role, when healthy, after the team appeared set to sign veteran Joe Mixon, ultimately backing out after his physical.
Jadarian Price - RB (chest)
Price was placed on injured reserve in Week 4.
Impact: Price played through the injury in Week 3 but apparently emerged worse off for wear. Emanuel Wilson and George Holani will split the backfield in his absence, although the biggest boost likely falls back to Jaxon Smith-Njigba.
George Holani - RB (ribs)
Holani was limited on Wednesday and is listed as questionable for Week 5 against the 49ers.
Impact: Holani could reprise a passing down role against the 49ers. He is not on the fantasy radar.
